| Literature DB >> 200333 |
S Hiraki, I Miyoshi, I Kubonishi, Y Matsuda, T Nakayama, H Kishimoto, H Masuji.
Abstract
A human lymphoblast cell line, NALL-1, was established from the peripheral blood of a patient with acute lymphoblastic leukemia (ALL). NALL-1 cells had neither properties of T and B cells nor Epstein-Barr virus (EBV). Many characteristics of the NALL-1 line were distinct from those of numerous EBV-positive lymphoblastoid cell lines previously reported. NALL-1 cells are considered to have originated from the donor's leukemic cells on the basis of their cytogenetic, morphologic and functional features. The NALL-1 line is the first human leukemic "null" cell line derived from ALL. The significance of this cell line is disscussed.Entities:
Mesh：
Year: 1977 PMID： 200333 DOI： 10.1002/1097-0142(197711)40:5<2131::aid-cncr2820400523>3.0.co;2-v
Source DB: PubMed Journal: Cancer ISSN： 0008-543X Impact factor: 6.860