Literature DB >> 7495980

Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer.

F van Leeuwen1, R Nusse.   

Abstract

In this short review, we will give an overview of the various genes that can be activated by insertion of proviral DNA of the mouse mammary tumor virus during the formation of mammary cancer. These genes fall within three families: Wnt genes, FGF genes and Notch-related genes. We will summarize our current understanding of the roles of these genes in tumorigenesis and in normal development, and the mechanisms of action of their gene products. Finally, we will give some examples of cooperation between these genes in various biological settings.

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Year:  1995        PMID: 7495980     DOI: 10.1006/scbi.1995.0018

Source DB:  PubMed          Journal:  Semin Cancer Biol        ISSN: 1044-579X            Impact factor:   15.707


  18 in total

1.  The c-myc locus is a common integration site in type B retrovirus-induced T-cell lymphomas.

Authors:  L Rajan; D Broussard; M Lozano; C G Lee; C A Kozak; J P Dudley
Journal:  J Virol       Date:  2000-03       Impact factor: 5.103

Review 2.  Adding to the mix: fibroblast growth factor and platelet-derived growth factor receptor pathways as targets in non-small cell lung cancer.

Authors:  S A Kono; L E Heasley; R C Doebele; D R Camidge
Journal:  Curr Cancer Drug Targets       Date:  2012-02       Impact factor: 3.428

3.  Sequence and genetic analyses of the 3' terminus and integration sites of the RIII/Sa mouse mammary tumor (MMTV) exogenous provirus.

Authors:  P Popken-Harris; L Pliml; L Harris
Journal:  Virus Genes       Date:  2001       Impact factor: 2.332

4.  Ku antigen-DNA conformation determines the activation of DNA-dependent protein kinase and DNA sequence-directed repression of mouse mammary tumor virus transcription.

Authors:  W Giffin; W Gong; C Schild-Poulter; R J Haché
Journal:  Mol Cell Biol       Date:  1999-06       Impact factor: 4.272

5.  Synergistic action of GA-binding protein and glucocorticoid receptor in transcription from the mouse mammary tumor virus promoter.

Authors:  K Aurrekoetxea-Hernández; E Buetti
Journal:  J Virol       Date:  2000-06       Impact factor: 5.103

6.  A compendium of the mouse mammary tumor biologist: from the initial observations in the house mouse to the development of genetically engineered mice.

Authors:  Robert D Cardiff; Nicholas Kenney
Journal:  Cold Spring Harb Perspect Biol       Date:  2011-06-01       Impact factor: 10.005

7.  Identification of Notch1 as a frequent target for provirus insertional mutagenesis in T-cell lymphomas induced by leukemogenic mutants of mouse mammary tumor virus.

Authors:  S Yanagawa; J S Lee; K Kakimi; Y Matsuda; T Honjo; A Ishimoto
Journal:  J Virol       Date:  2000-10       Impact factor: 5.103

8.  Rorgamma (Rorc) is a common integration site in type B leukemogenic virus-induced T-cell lymphomas.

Authors:  Dana R Broussard; Mary M Lozano; Jaquelin P Dudley
Journal:  J Virol       Date:  2004-05       Impact factor: 5.103

Review 9.  The fibroblast growth factor receptor signaling pathway as a mediator of intrinsic resistance to EGFR-specific tyrosine kinase inhibitors in non-small cell lung cancer.

Authors:  Scott A Kono; Marianne E Marshall; Kathryn E Ware; Lynn E Heasley
Journal:  Drug Resist Updat       Date:  2009-06-04       Impact factor: 18.500

10.  Transforming growth factor beta enhances the glucocorticoid response of the mouse mammary tumor virus promoter through Smad and GA-binding proteins.

Authors:  Koldo Aurrekoetxea-Hernández; Elena Buetti
Journal:  J Virol       Date:  2004-03       Impact factor: 5.103

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