| Literature DB >> 10666282 |
L Rajan1, D Broussard, M Lozano, C G Lee, C A Kozak, J P Dudley.
Abstract
Type B leukemogenic virus (TBLV) induces rapidly appearing T-cell leukemias. TBLV insertions near the c-myc gene were detectable in 2 of 30 tumors tested, whereas 80% of the tumors showed c-myc overexpression. TBLV insertions on chromosome 15 (including a newly identified locus, Pad7) may cause c-myc overexpression by cis-acting effects at a distance.Entities:
Mesh:
Year: 2000 PMID: 10666282 PMCID: PMC111733 DOI: 10.1128/jvi.74.5.2466-2471.2000
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103