Literature DB >> 10666282

The c-myc locus is a common integration site in type B retrovirus-induced T-cell lymphomas.

L Rajan1, D Broussard, M Lozano, C G Lee, C A Kozak, J P Dudley.   

Abstract

Type B leukemogenic virus (TBLV) induces rapidly appearing T-cell leukemias. TBLV insertions near the c-myc gene were detectable in 2 of 30 tumors tested, whereas 80% of the tumors showed c-myc overexpression. TBLV insertions on chromosome 15 (including a newly identified locus, Pad7) may cause c-myc overexpression by cis-acting effects at a distance.

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Year:  2000        PMID: 10666282      PMCID: PMC111733          DOI: 10.1128/jvi.74.5.2466-2471.2000

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  38 in total

1.  Chromosomal localization of acquired MMTV proviral integration sites in T-cell lymphomas.

Authors:  L Rajan; C A Kozak; J P Dudley
Journal:  Mamm Genome       Date:  1998-01       Impact factor: 2.957

2.  Mutational and functional analysis of the C-terminal region of the C3H mouse mammary tumor virus superantigen.

Authors:  T J Wrona; M Lozano; A A Binhazim; J P Dudley
Journal:  J Virol       Date:  1998-06       Impact factor: 5.103

3.  Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes.

Authors:  H Land; L F Parada; R A Weinberg
Journal:  Nature       Date:  1983 Aug 18-24       Impact factor: 49.962

4.  Acquisition of proviral DNA of mouse mammary tumor virus in thymic leukemia cells from GR mice.

Authors:  R Michalides; E Wagenaar; J Hilkens; J Hilgers; B Groner; N E Hynes
Journal:  J Virol       Date:  1982-09       Impact factor: 5.103

5.  Integration of type B retroviral DNA in virus-induced primary murine thymic lymphomas.

Authors:  G A Dekaban; J K Ball
Journal:  J Virol       Date:  1984-12       Impact factor: 5.103

6.  Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody.

Authors:  J P Allison; B W McIntyre; D Bloch
Journal:  J Immunol       Date:  1982-11       Impact factor: 5.422

7.  Exogenous mouse mammary tumor virus (MMTV) infection induces endogenous MMTV sag expression.

Authors:  L Xu; T J Wrona; J P Dudley
Journal:  Virology       Date:  1996-01-15       Impact factor: 3.616

8.  Amplification and novel locations of endogenous mouse mammary tumor virus genomes in mouse T-cell lymphomas.

Authors:  J Dudley; R Risser
Journal:  J Virol       Date:  1984-01       Impact factor: 5.103

9.  Purification and translation of murine mammary tumor virus mRNA's.

Authors:  J P Dudley; H E Varmus
Journal:  J Virol       Date:  1981-07       Impact factor: 5.103

Review 10.  Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer.

Authors:  F van Leeuwen; R Nusse
Journal:  Semin Cancer Biol       Date:  1995-06       Impact factor: 15.707

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  11 in total

1.  ALY is a common coactivator of RUNX1 and c-Myb on the type B leukemogenic virus enhancer.

Authors:  Jennifer A Mertz; Ryuji Kobayashi; Jaquelin P Dudley
Journal:  J Virol       Date:  2007-01-17       Impact factor: 5.103

2.  Analysis of wild-type and mutant SL3-3 murine leukemia virus insertions in the c-myc promoter during lymphomagenesis reveals target site hot spots, virus-dependent patterns, and frequent error-prone gap repair.

Authors:  Anne Ahlmann Nielsen; Annette Balle Sørensen; Jörg Schmidt; Finn Skou Pedersen
Journal:  J Virol       Date:  2005-01       Impact factor: 5.103

3.  Conversion of mouse mammary tumor virus to a lymphomagenic virus.

Authors:  Sanchita Bhadra; Mary M Lozano; Jaquelin P Dudley
Journal:  J Virol       Date:  2005-10       Impact factor: 5.103

4.  Substitution of feline leukemia virus long terminal repeat sequences into murine leukemia virus alters the pattern of insertional activation and identifies new common insertion sites.

Authors:  Chassidy Johnson; Patricia A Lobelle-Rich; Adriane Puetter; Laura S Levy
Journal:  J Virol       Date:  2005-01       Impact factor: 5.103

5.  Identification of Notch1 as a frequent target for provirus insertional mutagenesis in T-cell lymphomas induced by leukemogenic mutants of mouse mammary tumor virus.

Authors:  S Yanagawa; J S Lee; K Kakimi; Y Matsuda; T Honjo; A Ishimoto
Journal:  J Virol       Date:  2000-10       Impact factor: 5.103

6.  Selection for c-myc integration sites in polyclonal T-cell lymphomas.

Authors:  Dana R Broussard; Jennifer A Mertz; M Lozano; Jaquelin P Dudley
Journal:  J Virol       Date:  2002-03       Impact factor: 5.103

7.  The type B leukemogenic virus truncated superantigen is dispensable for T-cell lymphomagenesis.

Authors:  Farah Mustafa; Sanchita Bhadra; Dennis Johnston; Mary Lozano; Jaquelin P Dudley
Journal:  J Virol       Date:  2003-03       Impact factor: 5.103

8.  Rorgamma (Rorc) is a common integration site in type B leukemogenic virus-induced T-cell lymphomas.

Authors:  Dana R Broussard; Mary M Lozano; Jaquelin P Dudley
Journal:  J Virol       Date:  2004-05       Impact factor: 5.103

9.  Type B leukemogenic virus has a T-cell-specific enhancer that binds AML-1.

Authors:  J A Mertz; F Mustafa; S Meyers; J P Dudley
Journal:  J Virol       Date:  2001-03       Impact factor: 5.103

10.  Lessons Learned from Mouse Mammary Tumor Virus in Animal Models.

Authors:  Jaquelin P Dudley; Tatyana V Golovkina; Susan R Ross
Journal:  ILAR J       Date:  2016
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