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Literature DB >> 15078980

Rorgamma (Rorc) is a common integration site in type B leukemogenic virus-induced T-cell lymphomas.

Dana R Broussard¹, Mary M Lozano, Jaquelin P Dudley.

Abstract

The retrovirus type B leukemogenic virus (TBLV) causes T-cell lymphomas in mice. We have identified the Rorgamma locus as an integration site in 19% of TBLV-induced tumors. Overexpression of one or more Rorgamma isoforms in >77% of the tumors tested may complement apoptotic effects of c-myc overexpression.

Entities: Chemical Disease Gene Species

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Year: 2004 PMID： 15078980 PMCID： PMC387709 DOI： 10.1128/jvi.78.9.4943-4946.2004

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

36 in total

1. The c-myc locus is a common integration site in type B retrovirus-induced T-cell lymphomas.

Authors: L Rajan; D Broussard; M Lozano; C G Lee; C A Kozak; J P Dudley
Journal: J Virol Date: 2000-03 Impact factor: 5.103

Review 2. Role of the nuclear hormone receptor ROR gamma in transcriptional regulation, thymocyte survival, and lymphoid organogenesis.

Authors: D R Littman; Z Sun; D Unutmaz; M J Sunshine; H T Petrie; Y R Zou
Journal: Cold Spring Harb Symp Quant Biol Date: 1999

3. Requirement for RORgamma in thymocyte survival and lymphoid organ development.

Authors: Z Sun; D Unutmaz; Y R Zou; M J Sunshine; A Pierani; S Brenner-Morton; R E Mebius; D R Littman
Journal: Science Date: 2000-06-30 Impact factor: 47.728

4. Leukaemia disease genes: large-scale cloning and pathway predictions.

Authors: J Li; H Shen; K L Himmel; A J Dupuy; D A Largaespada; T Nakamura; J D Shaughnessy; N A Jenkins; N G Copeland
Journal: Nat Genet Date: 1999-11 Impact factor: 38.330

Review 5. The ROR nuclear orphan receptor subfamily: critical regulators of multiple biological processes.

Authors: A M Jetten; S Kurebayashi; E Ueda
Journal: Prog Nucleic Acid Res Mol Biol Date: 2001

Review 6. MMTV-induced mammary tumorigenesis: gene discovery, progression to malignancy and cellular pathways.

Authors: R Callahan; G H Smith
Journal: Oncogene Date: 2000-02-21 Impact factor: 9.867

7. Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis.

Authors: S Kurebayashi; E Ueda; M Sakaue; D D Patel; A Medvedev; F Zhang; A M Jetten
Journal: Proc Natl Acad Sci U S A Date: 2000-08-29 Impact factor: 11.205

8. Type B leukemogenic virus has a T-cell-specific enhancer that binds AML-1.

Authors: J A Mertz; F Mustafa; S Meyers; J P Dudley
Journal: J Virol Date: 2001-03 Impact factor: 5.103

9. Down-regulation of the orphan nuclear receptor ROR gamma t is essential for T lymphocyte maturation.

Authors: Y W He; C Beers; M L Deftos; E W Ojala; K A Forbush; M J Bevan
Journal: J Immunol Date: 2000-06-01 Impact factor: 5.422

10. RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells.

Authors: Y W He; M L Deftos; E W Ojala; M J Bevan
Journal: Immunity Date: 1998-12 Impact factor: 31.745

5 in total

Review 5. Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism.

Authors: Anton M Jetten
Journal: Nucl Recept Signal Date: 2009-04-03