Literature DB >> 7480182

Anti-diabetic effects of onion and garlic sulfoxide amino acids in rats.

C G Sheela, K Kumud, K T Augusti.   

Abstract

On oral administration of onion (Allium cepa L.) and garlic (A. sativum L.) sulfoxide amino acids viz., S-methylcysteine sulfoxide (SMCS) and S-allylcysteine sulfoxide (SACS) to alloxan-diabetic rats for a month, their diabetic condition, being characterized by glucose intolerance, weight loss, depletion of liver glycogen, etc., was ameliorated as comparable to rats treated with glibenclamide and insulin. However, only the last two drugs significantly increased the conversion of labelled acetate to liver cholesterol which indicates a deterrent effect of the allium products against the synthesis of a risk factor.

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Year:  1995        PMID: 7480182     DOI: 10.1055/s-2006-958099

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  25 in total

Review 1.  A review on the effects of Allium sativum (Garlic) in metabolic syndrome.

Authors:  A Hosseini; H Hosseinzadeh
Journal:  J Endocrinol Invest       Date:  2015-06-03       Impact factor: 4.256

2.  A rethinking on the benefits and drawbacks of common antioxidants and a proposal to look for the antioxidants in allium products as ideal agents: a review.

Authors:  K T Augusti; Regi Jose; G R Sajitha; Paul Augustine
Journal:  Indian J Clin Biochem       Date:  2011-08-09

3.  Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice.

Authors:  Wenqi Gao; Wei Wang; Jing Zhang; Pengyi Deng; Jun Hu; Jian Yang; Zhifang Deng
Journal:  Metab Brain Dis       Date:  2019-06-14       Impact factor: 3.584

4.  Effect of garlic powder on hippocampal long-term potentiation in rats fed high fat diet: an in vivo study.

Authors:  Iraj Salehi; Alireza Komaki; Seyed Asaad Karimi; Abdolrahman Sarihi; Mohammad Zarei
Journal:  Metab Brain Dis       Date:  2018-01-02       Impact factor: 3.584

5.  Effect of five cysteine-containing compounds on three lipogenic enzymes in Balb/cA mice consuming a high saturated fat diet.

Authors:  Chun-che Lin; Mei-chin Yin; Cheng-chin Hsu; Meng-pei Lin
Journal:  Lipids       Date:  2004-09       Impact factor: 1.880

Review 6.  Antidiabetic phytoconstituents and their mode of action on metabolic pathways.

Authors:  Sudhanshu Kumar Bharti; Supriya Krishnan; Ashwini Kumar; Awanish Kumar
Journal:  Ther Adv Endocrinol Metab       Date:  2018-02-12       Impact factor: 3.565

Review 7.  Mechanism of action of natural products used in the treatment of diabetes mellitus.

Authors:  Pranav Kumar Prabhakar; Mukesh Doble
Journal:  Chin J Integr Med       Date:  2011-08-09       Impact factor: 1.978

Review 8.  Herb-drug interactions: a literature review.

Authors:  Zeping Hu; Xiaoxia Yang; Paul Chi Lui Ho; Sui Yung Chan; Paul Wan Sia Heng; Eli Chan; Wei Duan; Hwee Ling Koh; Shufeng Zhou
Journal:  Drugs       Date:  2005       Impact factor: 9.546

9.  Organosulfur compounds and possible mechanism of garlic in cancer.

Authors:  S H Omar; N A Al-Wabel
Journal:  Saudi Pharm J       Date:  2009-12-24       Impact factor: 4.330

10.  Effect of herbal hypoglycemic agents on oxidative stress and antioxidant status in diabetic rats.

Authors:  Abbas Ali Mahdi; Anu Chandra; Raj Kumar Singh; Sanjeev Shukla; L C Mishra; Sohail Ahmad
Journal:  Indian J Clin Biochem       Date:  2003-07
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