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Literature DB >> 747398

Serum theophylline levels in asthmatic children after oral administration of two slow-release theophylline preparations.

Abstract

Serum theophylline levels were measured throughout the day in 65 asthmatic children receiving one of two slow-release theophylline compounds. There was a wide interindividual variation in levels obtained with similar doses of pure theophylline, and also a wide intraindividaual variation in levels throughout the day, suggesting that the rates of release and/or absorption of theophylline from these compounds are not uniform. There were fewer side effects associated with taking these compounds than with choline theophyllinate.

Entities: Chemical Species

Mesh：

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Year: 1978 PMID： 747398 PMCID： PMC1545169 DOI： 10.1136/adc.53.12.943

Source DB: PubMed Journal: Arch Dis Child ISSN： 0003-9888 Impact factor: 3.791

10 in total

1. FACTORS INFLUENCING THE RELEASE OF A DRUG FROM A PROLONGED-ACTION MATRIX.

Authors: J LAZARUS; M PAGLIERY; L LACHMAN
Journal: J Pharm Sci Date: 1964-07 Impact factor: 3.534

2. Relationship of theophylline clearance to oral dosage in children with chronic asthma.

Authors: E Ginchansky; M Weinberger
Journal: J Pediatr Date: 1977-10 Impact factor: 4.406

3. Pharmacokinetics of theophylline in children with asthma.

Authors: E F Ellis; R Koysooko; G Levy
Journal: Pediatrics Date: 1976-10 Impact factor: 7.124

4. Evaluation of oral bronchodilator therapy in asthmatic children. Bronchodilators in asthmatic children.

Authors: M M Weinberger; E A Bronsky
Journal: J Pediatr Date: 1974-03 Impact factor: 4.406

5. Pharmacokinetics of theophylline. Application to adjustment of the clinical dose of aminophylline.

Authors: J W Jenne; M S Wyze; F S Rood; F M MacDonald
Journal: Clin Pharmacol Ther Date: 1972 May-Jun Impact factor: 6.875

6. The effect of frequent administration of sodium cromoglycate to asthmatic children who previously responded poorly.

Authors: P König; S Godfrey
Journal: Clin Allergy Date: 1973-12

7. Compliance of chronic asthmatics with oral administration of theophylline as measured by serum and salivary levels.

Authors: R D Eney; E O Goldstein
Journal: Pediatrics Date: 1976-04 Impact factor: 7.124

8. Clinical applications of serum theophylline measurement by high pressure liquid chromatography.

Authors: S A McKenzie; A T Edmunds; E Baillie; J H Meek
Journal: Arch Dis Child Date: 1978-04 Impact factor: 3.791

9. Effect of practical timing of dosage on theophylline blood levels in asthmatic children treated with choline theophyllinate.

Authors: S A McKenzie; E Baillie; S Godfrey
Journal: Arch Dis Child Date: 1978-02 Impact factor: 3.791

10. Comparison of cromoglycate (cromolyn) and theophylline in controlling symptoms of chronic asthma. A collaborative study.

Authors: G Hambleton; M Weinberger; J Taylor; M Cavanaugh; E Ginchansky; S Godfrey; M Tooley; T Bell; S Greenberg
Journal: Lancet Date: 1977-02-19 Impact factor: 79.321

10 in total

15 in total

Serum theophylline levels in asthmatic children after oral administration of two slow-release theophylline preparations.

1. FACTORS INFLUENCING THE RELEASE OF A DRUG FROM A PROLONGED-ACTION MATRIX.

2. Relationship of theophylline clearance to oral dosage in children with chronic asthma.

3. Pharmacokinetics of theophylline in children with asthma.

4. Evaluation of oral bronchodilator therapy in asthmatic children. Bronchodilators in asthmatic children.

5. Pharmacokinetics of theophylline. Application to adjustment of the clinical dose of aminophylline.

6. The effect of frequent administration of sodium cromoglycate to asthmatic children who previously responded poorly.

7. Compliance of chronic asthmatics with oral administration of theophylline as measured by serum and salivary levels.

8. Clinical applications of serum theophylline measurement by high pressure liquid chromatography.

9. Effect of practical timing of dosage on theophylline blood levels in asthmatic children treated with choline theophyllinate.

10. Comparison of cromoglycate (cromolyn) and theophylline in controlling symptoms of chronic asthma. A collaborative study.

1. Current state of theophylline in asthma.

2. Childhood asthma: treatment and severity.

3. Bronchodilator drugs in childhood asthma.

4. Controlled trial of slow-release aminophylline in childhood asthma: are short-term trials valid?

5. Trial of cromoglycate and slow-release aminophylline in perennial childhood asthma.

Review 6. Management of asthma in the child aged under 6 years.

7. Nocturnal wheezing in children: management with controlled-release aminophylline.

Review 8. A clinical and pharmacokinetic basis for the selection and use of slow release theophylline products.

9. Slow release theophylline in preschool asthmatics.

10. A comparative trial of choline theophyllinate and controlled release aminophylline in chronic childhood asthma.