UNLABELLED: The aim of this study was to evaluate whether segments with reverse redistribution on rest-redistribution 201Tl scintigraphy represent viable tissue or scar. METHODS: Nineteen patients (17 men, 2 women; mean age 53 +/- 8 yr) with coronary artery disease underwent rest-redistribution 201Tl study before coronary revascularization. Regional 201Tl uptake was analyzed quantitatively. Regional left ventricular wall motion was assessed before and after coronary revascularization using two-dimensional echocardiography and a three-point scale (1 = normal, 2 = hypokinetic, 3 = akinetic/dyskinetic). Two patterns of reverse redistribution were identified: pattern with normal 201Tl uptake in rest and abnormal in redistribution images and pattern with abnormal 201Tl uptake in rest and a significant decrease in redistribution images. RESULTS: Of the 247 segments analyzed, 85 were classified as normal, 37 as reversible defects, 83 as fixed defects and 42 as reverse redistribution (19 RR-A, 23 RR-B). Segments with RR-A differed from those with RR-B in wall motion score (1.4 +/- 0.7 versus 2.0 +/- 1.0). Electrocardiographic Q-waves were present in 26% of segments with RR-A and in 57% of segments with pattern B. After revascularization, all dyssynergic segments with pattern A showed improved wall motion, while only 40% of segments with pattern B and abnormal wall motion had such improvement. CONCLUSION: Our results suggest that dyssynergic segments with pattern A should be considered viable, while more caution should be used in classifying those with pattern B.
UNLABELLED: The aim of this study was to evaluate whether segments with reverse redistribution on rest-redistribution 201Tl scintigraphy represent viable tissue or scar. METHODS: Nineteen patients (17 men, 2 women; mean age 53 +/- 8 yr) with coronary artery disease underwent rest-redistribution 201Tl study before coronary revascularization. Regional 201Tl uptake was analyzed quantitatively. Regional left ventricular wall motion was assessed before and after coronary revascularization using two-dimensional echocardiography and a three-point scale (1 = normal, 2 = hypokinetic, 3 = akinetic/dyskinetic). Two patterns of reverse redistribution were identified: pattern with normal 201Tl uptake in rest and abnormal in redistribution images and pattern with abnormal 201Tl uptake in rest and a significant decrease in redistribution images. RESULTS: Of the 247 segments analyzed, 85 were classified as normal, 37 as reversible defects, 83 as fixed defects and 42 as reverse redistribution (19 RR-A, 23 RR-B). Segments with RR-A differed from those with RR-B in wall motion score (1.4 +/- 0.7 versus 2.0 +/- 1.0). Electrocardiographic Q-waves were present in 26% of segments with RR-A and in 57% of segments with pattern B. After revascularization, all dyssynergic segments with pattern A showed improved wall motion, while only 40% of segments with pattern B and abnormal wall motion had such improvement. CONCLUSION: Our results suggest that dyssynergic segments with pattern A should be considered viable, while more caution should be used in classifying those with pattern B.
Authors: S Fujiwara; Y Takeishi; H Atsumi; M Yamaki; N Takahashi; M Yamaoka; T Tojo; H Tomoike Journal: J Nucl Cardiol Date: 1998 Mar-Apr Impact factor: 5.952
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Authors: M M Henneman; J D Schuijf; J W Jukema; H J Lamb; A de Roos; P Dibbets; M P Stokkel; E E van der Wall; J J Bax Journal: Heart Date: 2006-06-01 Impact factor: 5.994
Authors: Maureen M Henneman; Jeroen J Bax; Joanne D Schuijf; J Wouter Jukema; Eduard R Holman; Marcel P M Stokkel; Hildo J Lamb; Albert de Roos; Ernst E van der Wall Journal: Eur J Nucl Med Mol Imaging Date: 2006-07-25 Impact factor: 10.057
Authors: Ivan Jurić; Emir Fazlibegović; Danijel Pravdić; Boris Starčević; Ante Punda; Dražen Huić; Mustafa Hadžiomerović; Damir Rozić; Marko Martinac; Darko Markota; Mirjana Vasilj; Ivan Vasilj; Anshul Saxena Journal: Clin Med Insights Cardiol Date: 2018-07-23