Literature DB >> 7447406

Chemotherapy of Babesia microti infections in Mongolian Jirds.

T K Ruebush, P G Contacos, E A Steck.   

Abstract

For identifying drugs which might be effective in the treatment of human Babesia microti infections, 20 selected antiprotozoal agents or combinations of agents were tested for activity against B. microti in Mongolian jirds (meriones unguiculatus). 4-Methyl-primaquine and aromatic diamidines, including diminazene and pentamidine, were the most effective compounds tested.

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Year:  1980        PMID： 7447406      PMCID： PMC283985          DOI： 10.1128/AAC.18.2.289

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Human babesiosis on Nantucket Island. Evidence for self-limited and subclinical infections.

Authors:  T K Ruebush; D D Juranek; E S Chisholm; P C Snow; G R Healy; A J Sulzer
Journal:  N Engl J Med       Date:  1977-10-13       Impact factor: 91.245

2.  The antileishmanial activity of lepidines.

Authors:  K E Kinnamon; E A Steck; P S Loizeaux; W L Hanson; W L Chapman; V B Waits
Journal:  Am J Trop Med Hyg       Date:  1978-07       Impact factor: 2.345

3.  Entopolypoides macaci (Babesiidae) in Macaca mulatta.

Authors:  N N Gleason; R E Wolf
Journal:  J Parasitol       Date:  1974-10       Impact factor: 1.276

4.  Babesiosis in a Massachusetts resident.

Authors:  K A Western; G D Benson; N N Gleason; G R Healy; M G Schultz
Journal:  N Engl J Med       Date:  1970-10-15       Impact factor: 91.245

5.  Experimental Babesia microti infections in non-splenectomized Macaca mulatta.

Authors:  T K Ruebush; W E Collins; G R Healy; M Warren
Journal:  J Parasitol       Date:  1979-02       Impact factor: 1.276

6.  Neurologic complications following the treatment of human Babesia microti infection with diminazene aceturate.

Authors:  T K Ruebush; R H Rubin; E R Wolpow; P B Cassaday; M G Schultz
Journal:  Am J Trop Med Hyg       Date:  1979-03       Impact factor: 2.345

7.  Failure of chloroquine in human babesiosis (Babesia microti): case report and chemotherapeutic trials in hamsters.

Authors:  L H Miller; F A Neva; F Gill
Journal:  Ann Intern Med       Date:  1978-02       Impact factor: 25.391
  7 in total
  5 in total

1.  Novel diamidines with activity against Babesia divergens in vitro and Babesia microti in vivo.

Authors:  Angela Nehrbass-Stuedli; David Boykin; Richard R Tidwell; Reto Brun
Journal:  Antimicrob Agents Chemother       Date:  2011-05-02       Impact factor: 5.191

2.  Evaluation of selected antiprotozoal drugs in the Babesia microti-hamster model.

Authors:  S E Marley; M L Eberhard; F J Steurer; W L Ellis; P B McGreevy; T K Ruebush
Journal:  Antimicrob Agents Chemother       Date:  1997-01       Impact factor: 5.191

3.  Efficacy of the Antimalarial MMV390048 against Babesia Infection Reveals Phosphatidylinositol 4-Kinase as a Druggable Target for Babesiosis.

Authors:  Shengwei Ji; Eloiza May Galon; Mohamed Abdo Rizk; Yunpeng Yi; Iqra Zafar; Hang Li; Zhuowei Ma; Aiko Iguchi; Masahito Asada; Mingming Liu; Xuenan Xuan
Journal:  Antimicrob Agents Chemother       Date:  2022-08-04       Impact factor: 5.938

4.  Activities of artesunate-based combinations and tafenoquine against Babesia bovis in vitro and Babesia microti in vivo.

Authors:  Leonardo J M Carvalho; Bunduurem Tuvshintulga; Arifin B Nugraha; Thillaiampalam Sivakumar; Naoaki Yokoyama
Journal:  Parasit Vectors       Date:  2020-07-20       Impact factor: 3.876

Review 5.  Treatment of Human Babesiosis: Then and Now.

Authors:  Isaline Renard; Choukri Ben Mamoun
Journal:  Pathogens       Date:  2021-09-01
  5 in total

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