Literature DB >> 626449

Failure of chloroquine in human babesiosis (Babesia microti): case report and chemotherapeutic trials in hamsters.

L H Miller, F A Neva, F Gill.   

Abstract

The failure of a 3-week course of chloroquine to eliminate an infection of Babesia microti acquired on Martha's Vineyard led to tests of selected drugs in hamsters infected with the strain from this patient. The results showed response to several antitrypanosomal drugs (pentamidine and 4,4'-diazoaminobenzamidine) but not to antimalarial drugs (chloroquine, sulfadiazine, and pyrimethamine).

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Year:  1978        PMID： 626449     DOI： 10.7326/0003-4819-88-2-200

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN： 0003-4819            Impact factor:   25.391


  6 in total

1.  Babesiosis in man: a case from Scotland.

Authors:  J H Entrican; H Williams; I A Cook; W M Lancaster; J C Clark; L P Joyner; D Lewis
Journal:  Br Med J       Date:  1979-08-25

Review 2.  Chronic coinfections in patients diagnosed with chronic lyme disease: a systematic review.

Authors:  Paul M Lantos; Gary P Wormser
Journal:  Am J Med       Date:  2014-06-12       Impact factor: 4.965

3.  Novel diamidines with activity against Babesia divergens in vitro and Babesia microti in vivo.

Authors:  Angela Nehrbass-Stuedli; David Boykin; Richard R Tidwell; Reto Brun
Journal:  Antimicrob Agents Chemother       Date:  2011-05-02       Impact factor: 5.191

Review 4.  Babesiosis.

Authors:  M J Homer; I Aguilar-Delfin; S R Telford; P J Krause; D H Persing
Journal:  Clin Microbiol Rev       Date:  2000-07       Impact factor: 26.132

5.  Chemotherapy of Babesia microti infections in Mongolian Jirds.

Authors:  T K Ruebush; P G Contacos; E A Steck
Journal:  Antimicrob Agents Chemother       Date:  1980-08       Impact factor: 5.191

6.  Tafenoquine Is a Promising Drug Candidate for the Treatment of Babesiosis.

Authors:  Mingming Liu; Shengwei Ji; Daisuke Kondoh; Eloiza May Galon; Jixu Li; Mizuki Tomihari; Masashi Yanagawa; Michihito Tagawa; Mami Adachi; Masahito Asada; Ikuo Igarashi; Aiko Iguchi; Xuenan Xuan
Journal:  Antimicrob Agents Chemother       Date:  2021-06-17       Impact factor: 5.191
  6 in total

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