Literature DB >> 7437778

Generalised tissue abnormality of aryl hydrocarbon hydroxylase in psoriasis.

P H Chapman, P J Kersey, B Keys, S Shuster, M D Rawlins.   

Abstract

Microsomal aryl hydrocarbon hydroxylase (AHH) activity and inducibility were measured in jejunal mucosa, liver, and lesion-free epidermis of patients with psoriasis. In all three tissues AHH activity and inducibility were less than in controls. This demonstration of a generalised enzymatic abnormality in the tissues of patients with psoriasis is in keeping with the suggestion that it may be close to the underlying genetic defect.

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Year:  1980        PMID： 7437778      PMCID： PMC1714719          DOI： 10.1136/bmj.281.6251.1315

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  5 in total

1.  Arylhydrocarbon hydroxylase activity in lymphocytes of patients with psoriasis.

Authors:  T Ruzicka; W Vizethum; A Jacobs; G Goerz
Journal:  Lancet       Date:  1980-05-24       Impact factor: 79.321

2.  Psoriasis and cancer.

Authors:  S Shuster; P H Chapman; M D Rawlins
Journal:  Br Med J       Date:  1979-04-07

3.  Activity of aryl hydrocarbon hydroxylase in psoriatic skin.

Authors:  P H Chapman; M D Rawlins; S Shuster
Journal:  Lancet       Date:  1979-02-10       Impact factor: 79.321

4.  Decreased epidermal aryl hydrocarbon hydroxylase and localized pustular psoriasis.

Authors:  S Shuster; M D Rawlins; P H Chapman; S Rogers
Journal:  Br J Dermatol       Date:  1980-07       Impact factor: 9.302

5.  The activity of aryl hydrocarbon hydroxylase in adult human skin.

Authors:  P H Chapman; M D Rawlins; S Shuster
Journal:  Br J Clin Pharmacol       Date:  1979-05       Impact factor: 4.335
  5 in total
  10 in total

1.  Antipyrine clearance and metabolism in patients with psoriasis.

Authors:  K Kubota; T Ishizaki; K Chiba; A Takagi; A Nakagawa; K Nakamura
Journal:  Br J Clin Pharmacol       Date:  1986-10       Impact factor: 4.335

2.  Blood monocyte aryl hydrocarbon hydroxylase activity in psoriasis.

Authors:  G Mason; M D Rawlins; S Shuster
Journal:  Br J Clin Pharmacol       Date:  1983-09       Impact factor: 4.335

3.  Cytochrome P-450-dependent O-dealkylase activity in mammalian skin.

Authors:  F J Damen; P D Mier
Journal:  Br J Pharmacol       Date:  1982-01       Impact factor: 8.739

4.  Polymorphic 4-hydroxylation of debrisoquine in chronic discoid psoriasis.

Authors:  P H Chapman; M D Rawlins; S Shuster; J R Idle; J C Ritchie; R L Smith
Journal:  Eur J Clin Pharmacol       Date:  1981       Impact factor: 2.953

5.  Antipyrine clearance in psoriasis.

Authors:  P H Chapman; B Keys; M D Rawlins; C Moss; S Shuster
Journal:  Br Med J (Clin Res Ed)       Date:  1981-01-03

6.  Why not explore a possible link between psoriasis and cancer?

Authors:  J D Knox; E V Kuenssberg
Journal:  J R Coll Gen Pract       Date:  1981-05

7.  Psoriasis and cancer.

Authors:  P D Campion
Journal:  J R Coll Gen Pract       Date:  1983-05

8.  Aryl hydrocarbon hydroxylase activity in cultured lymphocytes of psoriatic patients.

Authors:  N T Kärki; J Karvonen; O Pelkonen
Journal:  Arch Dermatol Res       Date:  1982       Impact factor: 3.017

9.  Cancer incidence in patients with psoriasis.

Authors:  M R Alderson; J A Clarke
Journal:  Br J Cancer       Date:  1983-06       Impact factor: 7.640

10.  Human peripheral blood lymphocytes as a cell model to evaluate the genotoxic effect of coal tar treatment.

Authors:  S Pavanello; A G Levis
Journal:  Environ Health Perspect       Date:  1994-11       Impact factor: 9.031
  10 in total

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