| Literature DB >> 7435158 |
N R Ghatak, D Nochlin, M G Hadfield.
Abstract
We describe the fine structure of the subcortical neurofibrillary tangles (NFT) in 2 cases of progressive supranuclear palsy (PSP). In case 1 (69-year-old man) about one half of the NFT in the midbrain and pons examined were composed of 13-16 nm straight filaments and the other were made up of paired helical filaments (PHF) of Alzheimer type. The NFT in case 2 consisted of straight tubules with infrequent segments of unusual twisted fibril of unknown nature. The simultaneous occurrence of straight and PHF in one of these cases suggests that the NFT in PSP may be similar to those of Alzheimer type occurring in various conditions.Entities:
Mesh:
Year: 1980 PMID: 7435158 DOI: 10.1007/bf00687231
Source DB: PubMed Journal: Acta Neuropathol ISSN: 0001-6322 Impact factor: 17.088