Literature DB >> 7418850

Radiation-induced changes in gentamicin pharmacokinetics.

T Trnovec, S Bezek, J Navarová, M Gregusková, M Kettner, V Laginová.   

Abstract

Decreased clearance of i.v. or intratracheally administered gentamicin was observed in rats following single whole-body irradiation. 6 Gy 60Co. reaching its lowest rate on the 7th post-irradiation day. Simultaneously the absorption rate of gentamicin from the lungs was found to be increased.

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Year:  1980        PMID： 7418850     DOI： 10.1007/bf01965991

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  [Binding of sisomicin and gentamicin to serum proteins (author's transl)].

Authors:  H Rosenkranz; M Scheer; W Scholtan
Journal:  Arzneimittelforschung       Date:  1976

2.  Early effects of radiation on renal function in man.

Authors:  L V AVIOLI; M Z LAZOR; E COTLOVE; K C BRACE; J R ANDREWS
Journal:  Am J Med       Date:  1963-03       Impact factor: 4.965

3.  Distribution of gentamicin and amikacin in rabbit tissues.

Authors:  M L Kornguth; C M Kunin
Journal:  Antimicrob Agents Chemother       Date:  1977-06       Impact factor: 5.191

4.  GI drug absorption in rats exposed to cobalt-60-gamma-radiation III: in situ intestinal absorption.

Authors:  M E Brady; W L Hayton
Journal:  J Pharm Sci       Date:  1977-05       Impact factor: 3.534

5.  [Change in the tubular assimilation of Na plus and K plus in the human kidney under local cobalt 60 irridation. An immediate biological reaction with subsequent quick recovery?].

Authors:  H G Schmidt; F Dietzel; G Schirmer; A Caha; K Rödel; D Ringleb
Journal:  Strahlentherapie       Date:  1974-01

6.  Acute radiation effects in kidney.

Authors:  J C Hampton
Journal:  Radiat Res       Date:  1972-11       Impact factor: 2.841

7.  [Function and morphology of hypertrophic rabbit kidney after telecobalt-irradiation with 1000 to 4000 rad].

Authors:  G Bargon; H Mönch
Journal:  Strahlentherapie       Date:  1970-12

8.  Symposium on comparative and interactive effects of radiation and drugs. Opening remarks.

Authors:  V Nair
Journal:  Radiat Res       Date:  1967-02       Impact factor: 2.841

9.  [Formation of hemodynamic pulmonary edema in irradiated bodies].

Authors:  G V Kurygin; V N Kopylov; E F Girs; P A Chizhov
Journal:  Biull Eksp Biol Med       Date:  1978-09

10.  Pharmacokinetics of gentamicin administered intratracheally to rats.

Authors:  T Trnovec; J Navarová; M Kettner; M Gregusková; S Bezek; A Gajdosík; A Kyselová
Journal:  Antimicrob Agents Chemother       Date:  1978-08       Impact factor: 5.191
  10 in total

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