Literature DB >> 7418849

Examination of naturally occurring polyacetylenes and alpha-terthienyl for their ability to induce cytogenetic damage.

W D MacRae, G F Chan, C K Wat, G H Towers, J Lam.   

Abstract

alpha-Terthienyl and 5 polyacetylenes were examined for chromosome damaging activity using Syrian hamster cells. None of these naturally occurring compounds induced sister chromatid exchanges and neither alpha-terthienyl nor phenylheptatriyne induced chromosome aberrations.

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Year:  1980        PMID： 7418849     DOI： 10.1007/bf01965990

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  Ultraviolet-mediated cytotoxic activity of phenylheptatriyne from Bidens pilosa L.

Authors:  C K Wat; R K Biswas; E A Graham; L Bohm; G H Towers; E R Waygood
Journal:  J Nat Prod       Date:  1979 Jan-Feb       Impact factor: 4.050

2.  Induction of sister chromatid exchanges by UV light and its inhibition by caffeine.

Authors:  H Kato
Journal:  Exp Cell Res       Date:  1973-12       Impact factor: 3.905

3.  Phototoxicity evoked by alpha-terthienyl.

Authors:  G F Chan; M Prihoda; G H Towers; J C Mitchell
Journal:  Contact Dermatitis       Date:  1977-08       Impact factor: 6.600

4.  Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange.

Authors:  P Perry; H J Evans
Journal:  Nature       Date:  1975-11-13       Impact factor: 49.962

Review 5.  The search for relevant short term bioassays for chemical carcinogens: the tribulation of a modern Sisyphus.

Authors:  H F Stich; P Lam; L W Lo; D J Koropatnick; R H San
Journal:  Can J Genet Cytol       Date:  1975-12

6.  Phototoxic polyacetylenes and their thiophene derivatives. (Effects on human skin).

Authors:  G N Towers; T Arnason; C K Wat; E A Graham; J Lam; J L Mitchell
Journal:  Contact Dermatitis       Date:  1979-05       Impact factor: 6.600

7.  Cytogenetic assays of chemical clastogens using mammalian cells in culture.

Authors:  T C Hsu; C J Collie; A F Lusby; D A Johnston
Journal:  Mutat Res       Date:  1977-11       Impact factor: 2.433

8.  Ultraviolet-mediated antibiotic activity of species of Compositae caused by polyacetylenic compounds.

Authors:  G H Towers; C K Wat; E A Graham; R J Bandoni; G Q Chan; J C Mitchell; J Lam
Journal:  Lloydia       Date:  1977 Sep-Oct

9.  Sister chromatid exchanges induced in cultured mammalian cells by chromate.

Authors:  W D MacRae; R F Whiting; H F Stich
Journal:  Chem Biol Interact       Date:  1979-08       Impact factor: 5.192
  9 in total
  2 in total

1.  Berberine: A naturally occurring phototoxic alkaloid.

Authors:  B J Philogène; J T Arnason; G H Towers; Z Abramowski; F Campos; D Champagne; D McLachlan
Journal:  J Chem Ecol       Date:  1984-01       Impact factor: 2.626

2.  Distribution of thiophene derivatives in different organs of Tagetes patula seedlings grown under various conditions.

Authors:  R Sütfeld
Journal:  Planta       Date:  1982-01       Impact factor: 4.116
  2 in total

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