Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The metabolism of 8-methoxypsoralen in man.

Literature DB >> 7398681

The metabolism of 8-methoxypsoralen in man.

J Schmid, A Prox, A Reuter, H Zipp, F W Koss.

Abstract

8-Methoxypsoralen is metabolized rapidly and completely in man. Most of the metabolites presently known have their origin in a metabolic attack on the furan moiety yielding an aryl-diol and aryl-acetic-acid and are excreted as conjugates.

Entities: Chemical Species

Mesh：

Substances：
Methoxsalen

Year: 1980 PMID： 7398681 DOI： 10.1007/BF03189450

Source DB: PubMed Journal: Eur J Drug Metab Pharmacokinet ISSN： 0378-7966 Impact factor: 2.441

11 in total

1. Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light.

Authors: J A Parrish; T B Fitzpatrick; L Tanenbaum; M A Pathak
Journal: N Engl J Med Date: 1974-12-05 Impact factor: 91.245

2. Metabolism of coumarin in man.

Authors: W H Shilling; R F Crampton; R C Longland
Journal: Nature Date: 1969-02-15 Impact factor: 49.962

3. 2,3-Dihydro-2,3-dihydroxy-aflatoxin B1: an acid hydrolysis product of an RNA-aflatoxin B1 adduct formed by hamster and rat liver microsomes in vitro.

Authors: D H Swenson; J A Miller; E C Miller
Journal: Biochem Biophys Res Commun Date: 1973-08-21 Impact factor: 3.575

4. Metabolic reactions in vitro of psoralens with liver and epidermis.

Authors: B B Mandula; M A Pathak
Journal: Biochem Pharmacol Date: 1979 Impact factor: 5.858

Review 5. Biochemical and medical aspects of psoralens.

Authors: G Rodighiero; F Dall'Acqua
Journal: Photochem Photobiol Date: 1976-12 Impact factor: 3.421

6. The metabolism of 14C-methoxsalen by the dog.

Authors: S J Kolis; T H Williams; E J Postma; G J Sasso; P N Confalone; M A Schwartz
Journal: Drug Metab Dispos Date: 1979 Jul-Aug Impact factor: 3.922

7. Photochemotherapy: identification of a metabolite of 4, 5', 8-trimethylpsoralen.

Authors: B B Mandula; M A Pathak; G Dudek
Journal: Science Date: 1976-09-17 Impact factor: 47.728

8. Metabolic activation of furosemide to a chemically reactive, hepatotoxic metabolite.

Authors: J R Mitchell; W L Nelson; W Z Potter; H A Sasame; D J Jollow
Journal: J Pharmacol Exp Ther Date: 1976-10 Impact factor: 4.030

9. Metabolism of biphenyl in the rat.

Authors: K Halpaap; M G Horning; E C Horning
Journal: J Chromatogr Date: 1978-12-11

10. Pharmacokinetics and metabolite-pattern of 8-methoxypsoralen in man following oral administration as compared to the pharmacokinetics in rat and dog.

Authors: U Busch; J Schmid; F W Koss; H Zipp; A Zimmer
Journal: Arch Dermatol Res Date: 1978-08-28 Impact factor: 3.017

7 in total

1. Cytochrome P450-mediated metabolism of xanthotoxin by Papilio multicaudatus.

Authors: Wenfu Mao; Mark A Berhow; Arthur R Zangerl; Jennifer McGovern; May R Berenbaum
Journal: J Chem Ecol Date: 2006-03-30 Impact factor: 2.626

2. Fate of photosensitizing furanocoumarins in tolerant and sensitive insects.

Authors: D L Bull; G W Ivie; R C Beier; N W Pryor; E H Oertli
Journal: J Chem Ecol Date: 1984-06 Impact factor: 2.626

3. Fate of [(14)C]xanthotoxin (8-methoxypsoralen) in laying hens and a lactating goat.

Authors: N C Pangilinan; G W Ivie; B A Clement; R C Beier; M Uwayjan
Journal: J Chem Ecol Date: 1992-02 Impact factor: 2.626

4. Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor.

Authors: Jian Yang; Bingfang Yan
Journal: Toxicol Sci Date: 2006-09-26 Impact factor: 4.849