Literature DB >> 7395760

Evaluation of sensory irritation from some common industrial solvents.

L E Kane, R Dombroske, Y Alarie.   

Abstract

An animal bioassay model was used to determine the potency of some common industrial solvents as sensory irritants. Acetone was found to be the least potent and ethyl acetate the most potent. A series of alcohols tested, from methanol to pentanol, revealed an increase in potency with the increasing number of carbons.

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Year:  1980        PMID： 7395760     DOI： 10.1080/15298668091425022

Source DB:  PubMed          Journal:  Am Ind Hyg Assoc J        ISSN： 0002-8894


  9 in total

1.  Experimental data from closed chamber gas uptake studies in rodents suggest lower uptake rate of chemical than calculated from literature values on alveolar ventilation.

Authors:  G Johanson; J G Filser
Journal:  Arch Toxicol       Date:  1992       Impact factor: 5.153

2.  The effects of n-butanol vapour on respiratory rate and tidal volume.

Authors:  U Kristiansen; A M Vinggaard; G D Nielsen
Journal:  Arch Toxicol       Date:  1988-01       Impact factor: 5.153

3.  Short-term occupational exposure limits: a simplified approach.

Authors:  R L Zielhuis; P C Noordam; H Roelfzema; A A Wibowo
Journal:  Int Arch Occup Environ Health       Date:  1988       Impact factor: 3.015

4.  Irritation of the upper airways from mixtures of cumene and n-propanol. Mechanisms and their consequences for setting industrial exposure limits.

Authors:  G D Nielsen; U Kristiansen; L Hansen; Y Alarie
Journal:  Arch Toxicol       Date:  1988       Impact factor: 5.153

5.  Sensory irritation and pulmonary irritation of n-methyl ketones: receptor activation mechanisms and relationships with threshold limit values.

Authors:  L F Hansen; G D Nielsen
Journal:  Arch Toxicol       Date:  1994       Impact factor: 5.153

Review 6.  Local effects in the respiratory tract: relevance of subjectively measured irritation for setting occupational exposure limits.

Authors:  Josje H E Arts; Cees de Heer; Ruud A Woutersen
Journal:  Int Arch Occup Environ Health       Date:  2005-11-08       Impact factor: 3.015

Review 7.  Use of biological markers and pharmacokinetics in human health risk assessment.

Authors:  D Hattis
Journal:  Environ Health Perspect       Date:  1991-01       Impact factor: 9.031

8.  Dose-response analysis in animal studies: prediction of human responses.

Authors:  Y Alarie
Journal:  Environ Health Perspect       Date:  1981-12       Impact factor: 9.031

9.  Evaluation and application of the RD50 for determining acceptable exposure levels of airborne sensory irritants for the general public.

Authors:  Yu Kuwabara; George V Alexeeff; Rachel Broadwin; Andrew G Salmon
Journal:  Environ Health Perspect       Date:  2007-11       Impact factor: 9.031
  9 in total

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