Literature DB >> 7393223

Inhibition of exogenous mRNA translation in a cell-free system by chromatin peptides from calf thymus.

G L Gianfranceschi, M Hillar, J Przyjemski, D Amici, L Guglielmi.   

Abstract

Low molecular weight chromatin peptides isolated from calf thymus by affinity chromatography on DNA-cellulose inhibit significantly translation of exogenous isolated mRNA in a reticulocyte cell-free system. Translation with endogenous mRNA present in the system is not inhibited by low peptide concentrations. The data obtained combined with the previous findings suggest that chromatin peptides control gene expression at two levels: transcription and translation.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7393223     DOI： 10.1007/bf00775750

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  7 in total

1.  Stabilization of double-stranded DNA molecule by non-histone peptidic effector from calf thymus.

Authors:  G L Gianfranceschi; D Amici; L Guglielmi
Journal:  Mol Biol Rep       Date:  1976-09       Impact factor: 2.316

2.  Evidence for the presence in calf thymus of a peptidic factor controlling DNA transcription in vitro.

Authors:  G L Gianfranceschi; D Amici; L Guglielmi
Journal:  Biochim Biophys Acta       Date:  1975-11-18

3.  Restriction of template capacity of rat liver chromatin by a non-histone peptide from calf thymus.

Authors:  G L Gianfranceschi; D Amici; L Guglielmi
Journal:  Nature       Date:  1976-08-12       Impact factor: 49.962

4.  An efficient mRNA-dependent translation system from reticulocyte lysates.

Authors:  H R Pelham; R J Jackson
Journal:  Eur J Biochem       Date:  1976-08-01

5.  Low molecular weight peptides controlling transcription are present in the calf thymus chromatin structure.

Authors:  G L Gianfranceschi; L Guglielmi; D Amici; F Bossa; D Barra; R Petruzzelli
Journal:  Mol Biol Rep       Date:  1977-12       Impact factor: 2.316

6.  Control of transcription and translation by low molecular weight peptides (deprimerones) from chromatin and poly(A)-messenger RNA. Implication in the mechanism of carcinogenesis.

Authors:  M Hillar; J Przyjemski
Journal:  Biochim Biophys Acta       Date:  1979-09-27

7.  Low-molecular-weight peptide inhibits RNA synthesis in human leukemic and phytohemagglutinin-stimulated leukocytes and globin mRNA transcription in differentiating Friend cells.

Authors:  D Amici; G B Rossi; L Cioé; G P Matarese; A Dolei; L Guglielmi; G L Gianfranceschi
Journal:  Proc Natl Acad Sci U S A       Date:  1977-09       Impact factor: 11.205
  7 in total
  1 in total

1.  Studies on nuclear deprimerones: isolation, fractionation, characterization and control of gene expression.

Authors:  M Hillar; J Przyjemski; L E Wyborny
Journal:  Mol Biol Rep       Date:  1980-10-31       Impact factor: 2.316
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.