Literature DB >> 1034203

Stabilization of double-stranded DNA molecule by non-histone peptidic effector from calf thymus.

G L Gianfranceschi, D Amici, L Guglielmi.   

Abstract

A peptidic effector from calf thymus causes a strong stabilization of DNA double-stranded molecule in vitro. The active factor was isolated from aqueous ultrafiltered thymus extracts and purified by means of chromatography on DEAE-cellulose and then on Dowex 50 WX2. The purified thymic factor was characterized as a peptide of low molecular weight (less than 5000). The biological activity of the thymic factor cannot be attributed to a histone fragment. Melting data of the control DNA and of the DNA-active factor complex in various conditions of ionic strength and dielectric constant of the solution medium are recorded.

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Year:  1976        PMID： 1034203     DOI： 10.1007/BF00357209

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  15 in total

1.  Evidence for the presence in calf thymus of a peptidic factor controlling DNA transcription in vitro.

Authors:  G L Gianfranceschi; D Amici; L Guglielmi
Journal:  Biochim Biophys Acta       Date:  1975-11-18

2.  Regulation by thymus extracts of RNA synthesis in spleen cells "in vitro".

Authors:  D Amici; G L Gianfranceschi; L Guglielmi
Journal:  Boll Soc Ital Biol Sper       Date:  1975-11-15

3.  Aqueous extracts of thymus regulating the RNA and protein synthesis in E. Coli B.

Authors:  D Amici; G L Gianfranceschi
Journal:  Ital J Biochem       Date:  1974 May-Jun

4.  Co-operative binding of histones to DNA.

Authors:  R L Rubin; E N Moudrianakis
Journal:  J Mol Biol       Date:  1972-06-28       Impact factor: 5.469

5.  An aqueous thymus extract modifies DNA-proteins interactions in the liver of old rats. Spectrophotometrical data.

Authors:  G L Gianfranceschi; D Amici; L Guglielmi
Journal:  Experientia       Date:  1974-09-15

6.  Interaction of lysine-rich histones and DNA.

Authors:  D E Olins
Journal:  J Mol Biol       Date:  1969-08-14       Impact factor: 5.469

7.  Selective dissociation of histones from calf thymus nucleoprotein.

Authors:  H H Ohlenbusch; B M Olivera; D Tuan; N Davidson
Journal:  J Mol Biol       Date:  1967-04-28       Impact factor: 5.469

8.  Young and old rats. ATP, alkaline phosphatase, cholesterol and protein levels in the blood; DNA and RNA contents of the liver. Regulation by an aqueous thymus extract.

Authors:  D Amici; G L Gianfranceschi; G Marsili; L Michetti
Journal:  Experientia       Date:  1974-06-15

9.  Model nucleohistones: the interaction of F1 and F2al histones with native T7 DNA.

Authors:  D E Olins; A L Olins
Journal:  J Mol Biol       Date:  1971-05-14       Impact factor: 5.469

10.  Organ-specific restriction of transcription in mammalian chromatin.

Authors:  J Paul; R S Gilmour
Journal:  J Mol Biol       Date:  1968-07-14       Impact factor: 5.469
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  10 in total

1.  Specific thymic peptides-DNA interaction. Correlation with the possible stereochemical kinking scheme of DNA.

Authors:  L Guglielmi; G L Gianfranceschi; F Venanzi; A Polzonetti; D Amici
Journal:  Mol Biol Rep       Date:  1979-02-15       Impact factor: 2.316

2.  Control of RNA and protein synthesis in phytohemagglutinin-stimulated human lymphocytes by chromatin peptides from calf thymus.

Authors:  D Amici; G L Gianfranceschi
Journal:  Mol Biol Rep       Date:  1980-12-31       Impact factor: 2.316

3.  Thymic control of the polyploidization of hepatocytes during aging.

Authors:  C Pieri; C Giuli; C Bertoni-Freddari; L Piantanelli; I Z Nagy
Journal:  Experientia       Date:  1982-06-15

4.  Nuclear deprimerones in rat liver and Novikoff hepatoma.

Authors:  M Hillar; J Przyjemski
Journal:  Mol Biol Rep       Date:  1980-07-31       Impact factor: 2.316

5.  Inhibition of exogenous mRNA translation in a cell-free system by chromatin peptides from calf thymus.

Authors:  G L Gianfranceschi; M Hillar; J Przyjemski; D Amici; L Guglielmi
Journal:  Mol Biol Rep       Date:  1980-03-31       Impact factor: 2.316

6.  Low molecular weight peptides controlling transcription are present in the calf thymus chromatin structure.

Authors:  G L Gianfranceschi; L Guglielmi; D Amici; F Bossa; D Barra; R Petruzzelli
Journal:  Mol Biol Rep       Date:  1977-12       Impact factor: 2.316

7.  Effects of a chromatin low molecular weight peptidic fraction on differentiation markers and virus production in Friend leukemia cells.

Authors:  G B Rossi; L Cioe; S Pulciani; P Meo; F Titti; D Amici; G L Gianfranceschi
Journal:  Mol Biol Rep       Date:  1979-12-31       Impact factor: 2.316

8.  Low molecular weight peptidic fraction in the chromatin from normal and cancer cells: control of transcription.

Authors:  G L Gianfranceschi; M Hillar; J T Chan; D Amici
Journal:  Mol Biol Rep       Date:  1980-07-31       Impact factor: 2.316

9.  Low-molecular-weight peptide inhibits RNA synthesis in human leukemic and phytohemagglutinin-stimulated leukocytes and globin mRNA transcription in differentiating Friend cells.

Authors:  D Amici; G B Rossi; L Cioé; G P Matarese; A Dolei; L Guglielmi; G L Gianfranceschi
Journal:  Proc Natl Acad Sci U S A       Date:  1977-09       Impact factor: 11.205

10.  A class of DNA-binding peptides from wheat bud causes growth inhibition, G2 cell cycle arrest and apoptosis induction in HeLa cells.

Authors:  Loretta Mancinelli; Paula M De Angelis; Lucia Annulli; Valentina Padovini; Kjell Elgjo; Gian Luigi Gianfranceschi
Journal:  Mol Cancer       Date:  2009-07-31       Impact factor: 27.401
  10 in total

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