Literature DB >> 7387176

In vivo autoradiography and planimetry of epidermis in psoriatics under PUVA-therapy.

C Hofmann, M Landthaler, G Plewig, O Braun-Falco.   

Abstract

The effects of oral 8-methoxypsoralen-photochemotherapy (PUVA)-therapy) on involved epidermis of nine psoriatics and on normal skin of four control subjects was investigated by means of in vivo autoradiography and planimetry. Under PUVA-therapy there is a significant decrease of 3H-TdR labeled cells per epidermal cross-sectional surface, per length of basal membrane and per length of epidermal surface. There is also a significant decrease of epidermal thickness. In the initial phase of PUVA-therapy the decrease of 3H-TdR labeled cells is the most pronounced. The reduction of epidermal thickness is less than the decrease of 3H-TdR labeled cells.

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Year:  1980        PMID： 7387176     DOI： 10.1007/bf00416922

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  21 in total

1.  [Clinical experience with the 8-methoxypsoralen-UVA therapy (photochemotherapy) of psoriasis].

Authors:  C Hofmann; G Plewig; O Braun-Falco
Journal:  Hautarzt       Date:  1976-12       Impact factor: 0.751

2.  PUVA suppresses the proliferative stimulus produced by stripping on hairless mice.

Authors:  P O Fritsch; F Gschnait; G Kaaserer; W Brenner; S Chaikittisilpa; H Hönigsmann; K Wolff
Journal:  J Invest Dermatol       Date:  1979-08       Impact factor: 8.551

3.  Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light.

Authors:  J A Parrish; T B Fitzpatrick; L Tanenbaum; M A Pathak
Journal:  N Engl J Med       Date:  1974-12-05       Impact factor: 91.245

4.  Psoralen plus black light inhibits epidermal DNA synthesis.

Authors:  J F Walter; W H Kelsey; J J Voorhees; E A Duell
Journal:  Arch Dermatol       Date:  1973-06

5.  Autoradiographic in vitro-examination of psoriatic skin before, during and after dithranol treatment.

Authors:  G K Steigleder; H Schumann; K J Lennartz
Journal:  Arch Dermatol Forsch       Date:  1973

6.  Initial events in psoriasis: quantitative assessment.

Authors:  E Christophers; R Parzefall; O Braun-Falco
Journal:  Br J Dermatol       Date:  1973-10       Impact factor: 9.302

7.  Abnormal cell proliferation in psoriasis.

Authors:  G D Weinstein; P Frost
Journal:  J Invest Dermatol       Date:  1968-03       Impact factor: 8.551

8.  Autoradiographic analysis of turnover times of normal and psoriatic epidermis.

Authors:  G D Weinstein; E J Van Scott
Journal:  J Invest Dermatol       Date:  1965-10       Impact factor: 8.551

9.  [Technical experience with 8-methoxypsoralen photochemotherapy in common psoriasis].

Authors:  C Hofmann; G Plewig; O Braun-Falco
Journal:  Hautarzt       Date:  1976-06       Impact factor: 0.751

10.  [Beneficial effect of oral retinoid in psoriatic hyperproliferation. Autoradiographic studies on involved and non involved skin (author's transl)].

Authors:  E Dierlich; C E Orfanos; H Pullmann; G K Steigleder
Journal:  Arch Dermatol Res       Date:  1979-03-31       Impact factor: 3.017
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  3 in total

1.  Professor Dr. Dr. h. c. Otto Braun-Falco.

Authors: 
Journal:  Arch Dermatol Res       Date:  1987       Impact factor: 3.017

2.  Autoradiographic and planimetric analyses of the inflammatory infiltrate in psoriatic lesions under PUVA-therapy.

Authors:  M Landthaler; G Plewig; C Hofmann; O Braun-Falco
Journal:  Arch Dermatol Res       Date:  1980       Impact factor: 3.017

3.  Pityriasis rubra pilaris: a clinico-pathological and therapeutic study with special reference to histochemistry, autoradiography, and electron microscopy.

Authors:  O Braun-Falco; F Ryckmanns; C Schmoeckel; M Landthaler
Journal:  Arch Dermatol Res       Date:  1983       Impact factor: 3.017
  3 in total

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