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Literature DB >> 7447490

Autoradiographic and planimetric analyses of the inflammatory infiltrate in psoriatic lesions under PUVA-therapy.

M Landthaler, G Plewig, C Hofmann, O Braun-Falco.

Abstract

The effects of oral 8-methoxypsoralen-photochemotherapy (PUVA-therapy) on the inflammatory infiltrate in 14 psoriatic skin lesions and on normal skin of 7 controls were investigated by means of autoradiography and planimetry. Under PUVA-therapy, one finds a significant decrease in dermal cells per millimeter lesion in psoriasis. Percentage of 3H-TdR-labeled dermal cells in the lesions and total number of dermal cells in the control group do not change significantly. The relative decrease of dermal cells per millimeter lesion in psoriasis is far less significant than the reduction of 3H-TdR-labeled epidermal cells under PUVA-therapy.

Entities: Chemical Disease

Mesh：

Year: 1980 PMID： 7447490 DOI： 10.1007/bf00404455

Source DB: PubMed Journal: Arch Dermatol Res ISSN： 0340-3696 Impact factor: 3.017

21 in total

1. [Clinical experience with the 8-methoxypsoralen-UVA therapy (photochemotherapy) of psoriasis].

Authors: C Hofmann; G Plewig; O Braun-Falco
Journal: Hautarzt Date: 1976-12 Impact factor: 0.751

2. [Photochemotherapy in mycosis fungoides].

Authors: K Konrad; F Gschnait; H Hönigsmann; P Fritsch; K Wolff
Journal: Hautarzt Date: 1978-04 Impact factor: 0.751

3. Photochemotherapy for psoriasis. A clinical cooperative study of PUVA-48 and PUVA-64.

Authors:
Journal: Arch Dermatol Date: 1979-05

4. PUVA suppresses the proliferative stimulus produced by stripping on hairless mice.

Authors: P O Fritsch; F Gschnait; G Kaaserer; W Brenner; S Chaikittisilpa; H Hönigsmann; K Wolff
Journal: J Invest Dermatol Date: 1979-08 Impact factor: 8.551

5. Comparative study of 3 H-thymidine labelling of the dermal infiltrate of skin allergic and irritant patch test reactions in man.

Authors: J M Lachapelle
Journal: Br J Dermatol Date: 1972-11 Impact factor: 9.302

2. Pityriasis rubra pilaris: a clinico-pathological and therapeutic study with special reference to histochemistry, autoradiography, and electron microscopy.

Authors: O Braun-Falco; F Ryckmanns; C Schmoeckel; M Landthaler
Journal: Arch Dermatol Res Date: 1983 Impact factor: 3.017

2 in total

Autoradiographic and planimetric analyses of the inflammatory infiltrate in psoriatic lesions under PUVA-therapy.

1. [Clinical experience with the 8-methoxypsoralen-UVA therapy (photochemotherapy) of psoriasis].

2. [Photochemotherapy in mycosis fungoides].

3. Photochemotherapy for psoriasis. A clinical cooperative study of PUVA-48 and PUVA-64.

4. PUVA suppresses the proliferative stimulus produced by stripping on hairless mice.

5. Comparative study of 3 H-thymidine labelling of the dermal infiltrate of skin allergic and irritant patch test reactions in man.

6. The dermal inflammatory reaction in initial psoriatic lesions.

7. [Light microscopy studies in the photochemotherapy of psoriasis vulgaris].

8. UVA-induced inhibition of proliferation of PHA-stimulated lymphocytes from humans treated with 8-methoxypsoralen.

9. Evaluation of PUVA, topical corticosteroids and the combination of both in the treatment of psoriasis.

10. Lymphocyte proliferation during PUVA therapy.

1. Professor Dr. Dr. h. c. Otto Braun-Falco.

2. Pityriasis rubra pilaris: a clinico-pathological and therapeutic study with special reference to histochemistry, autoradiography, and electron microscopy.