Literature DB >> 7335119

[Lectins, toxins and immunotoxins].

G Uhlenbruck.   

Abstract

A definition and classification of lectins (carbohydrate-binding (glyco)proteins) is given on the basis of new data and experimental results. Especially the biological role of bacterial, vertebrate and sponge lectins is discussed. The lectin-toxin combination offers an excellent model not only for studying adhesion to and penetration through the cell membrane, but also for hybridization with antibody fragments showing anti-tumor specificity.

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Year:  1981        PMID： 7335119     DOI： 10.1007/bf00398611

Source DB:  PubMed          Journal:  Naturwissenschaften        ISSN： 0028-1042


  41 in total

1.  Aggregation of sponge cells. Function of a lectin in its homologous biological system.

Authors:  W E Müller; B Kurelec; R K Zahn; I Müller; P Vaith; G Uhlenbruck
Journal:  J Biol Chem       Date:  1979-08-25       Impact factor: 5.157

Review 2.  [Biology of lectins and their application in clinical biochemistry (author's transl)].

Authors:  E Köttgen
Journal:  Klin Wochenschr       Date:  1977-04-15

3.  Mechanism of action of the toxic lectins abrin and ricin.

Authors:  S Olsnes; K Refsnes; A Pihl
Journal:  Nature       Date:  1974-06-14       Impact factor: 49.962

4.  Purification and characterization of a species-specific aggregation factor in sponges.

Authors:  W E Müller; R K Zahn
Journal:  Exp Cell Res       Date:  1973-07       Impact factor: 3.905

5.  Dimensions and specificities of recognition sites on lectins and antibodies.

Authors:  E A Kabat
Journal:  J Supramol Struct       Date:  1978

6.  Histochemical methods for the demonstration of Thomsen-Friedenreich antigen in cell suspensions and tissue sections.

Authors:  P J Klein; R A Newman; P Müller; G Uhlenbruck; H E Schaefer; K J Lennartz; R Fischer
Journal:  Klin Wochenschr       Date:  1978-08-01

7.  [Lectins: introduction, developments and perspectives].

Authors:  G Uhlenbruck
Journal:  J Clin Chem Clin Biochem       Date:  1980-06

8.  Studies on the fate of defined asialoglycoproteins in the circulation of the mouse.

Authors:  R A Newman; U Fricke; P J Klein; G Uhlenbruck; A L De Vries
Journal:  J Clin Chem Clin Biochem       Date:  1980-01

9.  Studies on cell adhesion and recognition. I. Extent and specificity of cell adhesion triggered by carbohydrate-reactive proteins (glycosidases and lectins) and by fibronectin.

Authors:  H Rauvala; W G Carter; S I Hakomori
Journal:  J Cell Biol       Date:  1981-01       Impact factor: 10.539

10.  Studies on cell adhesion and recognition. II. The kinetics of cell adhesion and cell spreading on surfaces coated with carbohydrate-reactive proteins (glycosidases and lectins) and fibronectin.

Authors:  W G Carter; H Rauvala; S I Hakomori
Journal:  J Cell Biol       Date:  1981-01       Impact factor: 10.539
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  3 in total

Review 1.  [Tumor lectinology--status and perspectives of clinical application].

Authors:  H J Gabius; S Gabius
Journal:  Naturwissenschaften       Date:  1990-11

2.  Membrane lectins in human malignant melanoma.

Authors:  H J Gabius; K Vehmeyer
Journal:  Naturwissenschaften       Date:  1987-01

3.  Comparative study of procedures for histological detection of lectin binding by use of Griffonia simplicifolia agglutinin I and gastrointestinal mucosa of the rat.

Authors:  W D Kuhlmann; P Peschke
Journal:  Histochemistry       Date:  1984
  3 in total

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