Literature DB >> 682531

Histochemical methods for the demonstration of Thomsen-Friedenreich antigen in cell suspensions and tissue sections.

P J Klein, R A Newman, P Müller, G Uhlenbruck, H E Schaefer, K J Lennartz, R Fischer.   

Abstract

1. Three different methods are described for the visualisation of the Thomsen-Friedenreich (TF) antigen on cell suspensions, formalin-fixed and paraffin embedded or frozen tissue sections: a) Rosette formation with chicken and sheep erythrocytes. b) Fluorescence-microscopy with fluorescein labelled peanut agglutinin. c) Autoradiography with 3H-labelled peanut agglutinin. 2. The TF antigen was shown, as far as presently investigated, to be exposed on various blood cells, glomerula of the kidney and normal mammary gland after neuraminidase treatment. Mammary gland was also shown to possess TF receptors without prior treatment with neuraminidase. 3. The exposure of this cryptantigen can be brought about by bacterial or viral neuraminidase and is followed by an antigen/antibody reaction, which can lead to possible pathological consequences.

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Year:  1978        PMID： 682531     DOI： 10.1007/BF01476765

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN： 0023-2173


  13 in total

1.  FACTORS AFFECTING THE RATE OF REACTION OF FLUORESCEIN ISOTHIOCYANATE WITH SERUM PROTEINS.

Authors:  R M MCKINNEY; J T SPILLANE; G W PEARCE
Journal:  J Immunol       Date:  1964-08       Impact factor: 5.422

2.  Blood group MN antigens and precursors in normal and malignant human breast glandular tissue.

Authors:  G F Springer; P R Desai; I Banatwala
Journal:  J Natl Cancer Inst       Date:  1975-02       Impact factor: 13.506

3.  Further studies on the interaction of lectins with human serum glycoproteins.

Authors:  G Uhlenbruck; R Newman; G Steinhausen; H G Schwick
Journal:  Z Immunitatsforsch Immunobiol       Date:  1977-07

4.  Investigation into the occurrence and structure of lectin receptors on human and bovine erythrocytes milk fat globule and lymphocyte plasma-membrane glycoproteins.

Authors:  R A Newman; G G Uhlenbruck
Journal:  Eur J Biochem       Date:  1977-06-01

5.  [Demonstration of breast neoplasm cells by means of the immunofluorescence technic].

Authors:  K Fischer; A Poschmann; H E Stegner
Journal:  Dtsch Med Wochenschr       Date:  1977-08-26       Impact factor: 0.628

6.  [Studies on the T-antigen and T-agglutinin].

Authors:  Z Kim; G Uhlenbruck
Journal:  Z Immunitatsforsch Allerg Klin Immunol       Date:  1966-01

7.  [Severe pneumonia with hemolysis caused by neuraminidase. Detection of cryptantigens by indirect immunofluorescent technic].

Authors:  K Fischer; A Poschmann; H Oster
Journal:  Monatsschr Kinderheilkd       Date:  1971-01

8.  Autoradiographic detection of antigens in cells using tritium-labeled antibodies.

Authors:  K Ostrowski; E A Barnard; W Sawicki; T Chorzelski; A Langner; A Mikulski
Journal:  J Histochem Cytochem       Date:  1970-07       Impact factor: 2.479

9.  Alkali-labile oligosaccharides from glycoproteins of different erythrocyte and milk fat globule membranes.

Authors:  W M Glöckner; R A Newman; W Dahr; G Uhlenbruck
Journal:  Biochim Biophys Acta       Date:  1976-09-07

10.  The purification, composition, and specificity of the anti-T lectin from peanut (Arachis hypogaea).

Authors:  R Lotan; E Skutelsky; D Danon; N Sharon
Journal:  J Biol Chem       Date:  1975-11-10       Impact factor: 5.157
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  19 in total

1.  Lectin binding sites in cultured human breast cancer cells.

Authors:  E Müller-Holzner; C Marth; E Kofler; G Daxenbichler; F Hofstädter
Journal:  Breast Cancer Res Treat       Date:  1985       Impact factor: 4.872

2.  Comparative histological, histochemical, immunohistochemical and biochemical studies on oestrogen receptors, lectin receptors, and Barr bodies in human breast cancer.

Authors:  W Remmele; U Hildebrand; H A Hienz; P J Klein; M Vierbuchen; L J Behnken; B Heicke; E Scheidt
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

3.  Griffonia simplicifolia lectins bind specifically to endothelial cells and some epithelial cells in mouse tissues.

Authors:  L Laitinen
Journal:  Histochem J       Date:  1987-04

4.  Extracellular matrix promotes mammary epithelial growth and differentiation in vitro.

Authors:  M S Wicha; G Lowrie; E Kohn; P Bagavandoss; T Mahn
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

5.  [Lectins, toxins and immunotoxins].

Authors:  G Uhlenbruck
Journal:  Naturwissenschaften       Date:  1981-12

6.  Lectin binding sites in the choroid plexus and choroid plexus papillomas.

Authors:  W Müller; P J Klein; M J Vierbuchen; G Uhlenbruck
Journal:  Neurosurg Rev       Date:  1980       Impact factor: 3.042

7.  A method for T-antigen demonstration by a polyclonal antibody and peanut lectin; elimination of cross-reaction with naturally occurring antibodies.

Authors:  T F Orntoft
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1984

8.  Tumor therapy of neoplastic diseases with tumor cells and neuraminidase. Further experimental studies on chessboard vaccination in canine mammary tumors.

Authors:  H H Sedlacek; G Hagmayer; F R Seiler
Journal:  Cancer Immunol Immunother       Date:  1986       Impact factor: 6.968

9.  In vivo localization of radioiodinated peanut lectin in a murine TA3/Ha mammary carcinoma model.

Authors:  A Shysh; S M Eu; A A Noujaim; M R Suresh; B M Longenecker
Journal:  Eur J Nucl Med       Date:  1985

10.  Isolation and chemical and immunochemical characterization of the peanut-lectin-binding glycoprotein from human milk-fat-globule membranes.

Authors:  J Fischer; P J Klein; G H Farrar; F G Hanisch; G Uhlenbruck
Journal:  Biochem J       Date:  1984-12-01       Impact factor: 3.857
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