Literature DB >> 7306012

GDP binding to brown-adipose-tissue mitochondria of diabetic--obese (db/db) mice. Decreased binding in both the obese and pre-obese states.

A E Goodbody, P Trayhurn.   

Abstract

GDP binding to brown-adipose-tissue mitochondria from adult diabetic--obese (db/db) mice was significantly less than with lean siblings. Binding was also decreased in the mutant mice before obesity had begun to develop. Decreased GDP binding was found to result from a decrease in the number of binding sites.

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Year:  1981        PMID: 7306012      PMCID: PMC1162842          DOI: 10.1042/bj1941019

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  22 in total

1.  A colorimetric method for the determination of deoxyribonucleic acid in adipose tissue.

Authors:  P B Curtis-Prior; T Hanley; N J Temple
Journal:  Analyst       Date:  1975-02       Impact factor: 4.616

2.  STUDIES ON CYTOCHROME OXIDASE. VI. KINETICS OF THE AEROBIC OXIDATION OF FERROCYTOCHROME C BY CYTOCHROME OXIDASE.

Authors:  T YONETANI; G S RAY
Journal:  J Biol Chem       Date:  1965-08       Impact factor: 5.157

3.  Binding of guanine nucleotides to the outer surface of the inner membrane of guinea pig brown fat mitochondria in correlation with the thermogenic activity of the tissue.

Authors:  J Rafael; H W Heldt
Journal:  FEBS Lett       Date:  1976-04-01       Impact factor: 4.124

4.  A simplified method for the quantitative assay of small amounts of protein in biologic material.

Authors:  G R Schacterle; R L Pollack
Journal:  Anal Biochem       Date:  1973-02       Impact factor: 3.365

5.  A role for brown adipose tissue in diet-induced thermogenesis.

Authors:  N J Rothwell; M J Stock
Journal:  Nature       Date:  1979-09-06       Impact factor: 49.962

6.  Regional blood flow in genetically obese (ob/ob) mice. The importance of brown adipose tissue to the reduced energy expenditure on non-shivering thermogenesis.

Authors:  P L Thurlby; P Trayhurn
Journal:  Pflugers Arch       Date:  1980-06       Impact factor: 3.657

7.  Hamster brown-adipose-tissue mitochondria. Purine nucleotide control of the ion conductance of the inner membrane, the nature of the nucleotide binding site.

Authors:  D G Nicholls
Journal:  Eur J Biochem       Date:  1976-02-16

8.  Thermoregulation in the diabetic-obese (db/db) mouse. The role of non-shivering thermogenesis in energy balance.

Authors:  P Trayhurn
Journal:  Pflugers Arch       Date:  1979-07       Impact factor: 3.657

9.  The development of obesity in genetically diabetic-obese (db/db) mice pair-fed with lean siblings. The importance of thermoregulatory thermogenesis.

Authors:  P Trayhurn; L Fuller
Journal:  Diabetologia       Date:  1980-08       Impact factor: 10.122

10.  The role of thermoregulatory thermogenesis in the development of obesity in genetically-obese (ob/ob) mice pair-fed with lean siblings.

Authors:  P L Thurlby; P Trayhurn
Journal:  Br J Nutr       Date:  1979-11       Impact factor: 3.718

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  23 in total

1.  Functional atrophy of brown adipose tissue during lactation in mice. Effects of lactation and weaning on mitochondrial GDP binding and uncoupling protein.

Authors:  P Trayhurn; G Jennings
Journal:  Biochem J       Date:  1987-11-15       Impact factor: 3.857

2.  Effect of polyunsaturated fatty acids in obese mice.

Authors:  M T Clandinin; S Cheema; D Pehowich; C J Field
Journal:  Lipids       Date:  1996-03       Impact factor: 1.880

3.  The effects of corticosterone, cold exposure and overfeeding with sucrose on brown adipose tissue of obese Zucker rats (fa/fa).

Authors:  S Holt; D A York; J T Fitzsimons
Journal:  Biochem J       Date:  1983-07-15       Impact factor: 3.857

4.  GDP binding to brown-adipose-tissue mitochondria of mice treated chronically with corticosterone.

Authors:  K S Galpin; R G Henderson; W P James; P Trayhurn
Journal:  Biochem J       Date:  1983-07-15       Impact factor: 3.857

5.  Evidence for a high fatty acid synthesis activity in interscapular brown adipose tissue of genetically obese Zucker rats.

Authors:  M Lavau; R Bazin; Z Karaoghlanian; C Guichard
Journal:  Biochem J       Date:  1982-05-15       Impact factor: 3.857

6.  Evidence for decreased GDP binding to brown-adipose-tissue mitochondria of obese Zucker (fa/fa) rats in the very first days of life.

Authors:  R Bazin; D Eteve; M Lavau
Journal:  Biochem J       Date:  1984-07-01       Impact factor: 3.857

7.  Mitochondrial Ca2+ transport in lean and genetically obese (ob/ob) mice.

Authors:  D R Fraser; P Trayhurn
Journal:  Biochem J       Date:  1983-07-15       Impact factor: 3.857

8.  The influence of GDP on Ca2+ uptake by mitochondria of brown adipose tissue from lean and genetically obese (ob/ob) mice.

Authors:  P Trayhurn; D R Fraser
Journal:  Biochem J       Date:  1983-07-15       Impact factor: 3.857

9.  The effect of adrenalectomy on GDP binding to brown-adipose-tissue mitochondria of obese rat.

Authors:  S Holt; D A York
Journal:  Biochem J       Date:  1982-12-15       Impact factor: 3.857

10.  Developmental changes in fatty acid synthesis in interscapular brown adipose tissue of lean and genetically obese (ob/ob) mice.

Authors:  S W Mercer; P Trayhurn
Journal:  Biochem J       Date:  1983-05-15       Impact factor: 3.857

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