Literature DB >> 7305432

Percutaneous absorption of chlorhexidine in neonatal cord care.

P J Aggett, L V Cooper, S H Ellis, J McAinsh.   

Abstract

The percutaneous absorption of chlorhexidine during its routine use in topical antiseptic preparations used in umbilical cord care was investigated by determining plasma chlorhexidine concentrations at ages 5 and 9 days. These showed that percutaneous absorption of chlorhexidine occurred in preterm neonates treated with a 1% solution of chlorhexidine in ethanol, but not in term infants similarly treated, or in preterm infants treated only with a dusting powder containing 1% chlorhexidine and 3% zinc oxide.

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Year:  1981        PMID： 7305432      PMCID： PMC1627378          DOI： 10.1136/adc.56.11.878

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  7 in total

1.  The use of chlorhexidine.

Authors:  H BEEUWKES
Journal:  Antonie Van Leeuwenhoek       Date:  1958       Impact factor: 2.271

2.  Clinical pharmacology of hexachlorophene in newborn infants.

Authors:  E E Tyrala; L S Hillman; R E Hillman; W E Dodson
Journal:  J Pediatr       Date:  1977-09       Impact factor: 4.406

3.  Increased skin permeability in preterm infants.

Authors:  R L Nachman; N B Esterly
Journal:  J Pediatr       Date:  1971-10       Impact factor: 4.406

4.  Clinical assessment of gestational age in the newborn infant.

Authors:  L M Dubowitz; V Dubowitz; C Goldberg
Journal:  J Pediatr       Date:  1970-07       Impact factor: 4.406

5.  Comparison of hexachlorophane and chlorhexidine powders in prevention of neonatal infection.

Authors:  V G Alder; D Burman; R A Simpson; J Fysh; W A Gillespie
Journal:  Arch Dis Child       Date:  1980-04       Impact factor: 3.791

6.  Absorption of chlorhexidine from the intact skin of newborn infants.

Authors:  J Cowen; S H Ellis; J McAinsh
Journal:  Arch Dis Child       Date:  1979-05       Impact factor: 3.791

7.  Use of 4 per cent chlorhexidine detergent solution (Hibiscrub) and other methods of skin disinfection.

Authors:  E J Lowbury; H A Lilly
Journal:  Br Med J       Date:  1973-03-03
  7 in total
  13 in total

Review 1.  Safety and impact of chlorhexidine antisepsis interventions for improving neonatal health in developing countries.

Authors:  Luke C Mullany; Gary L Darmstadt; James M Tielsch
Journal:  Pediatr Infect Dis J       Date:  2006-08       Impact factor: 2.129

2.  In vivo biocompatibility and in vitro efficacy of antimicrobial gendine-coated central catheters.

Authors:  Mohamed A Jamal; Ray Y Hachem; Joel Rosenblatt; Mark J McArthur; Edd Felix; Ying Jiang; Ramesh C Tailor; Issam Raad
Journal:  Antimicrob Agents Chemother       Date:  2015-06-29       Impact factor: 5.191

Review 3.  Antiseptic use in the neonatal intensive care unit - a dilemma in clinical practice: An evidence based review.

Authors:  Sundar Sathiyamurthy; Jayanta Banerjee; Sunit V Godambe
Journal:  World J Clin Pediatr       Date:  2016-05-08

4.  Tolerance and safety of different concentrations of chlorhexidine for peripartum vaginal and infant washes: HIVNET 025.

Authors:  Craig M Wilson; Glenda Gray; Jennifer S Read; Anthony Mwatha; Sanjay Lala; Saul Johnson; Avye Violari; Portia Mabali Sibiya; Thomas R Fleming; Ann Koonce; Sten H Vermund; James McIntyre
Journal:  J Acquir Immune Defic Syndr       Date:  2004-02-01       Impact factor: 3.731

Review 5.  Topical umbilical cord care at birth.

Authors:  J Zupan; P Garner; A A A Omari
Journal:  Cochrane Database Syst Rev       Date:  2004

6.  Topical applications of chlorhexidine to the umbilical cord for prevention of omphalitis and neonatal mortality in southern Nepal: a community-based, cluster-randomised trial.

Authors:  Luke C Mullany; Gary L Darmstadt; Subarna K Khatry; Joanne Katz; Steven C LeClerq; Shardaram Shrestha; Ramesh Adhikari; James M Tielsch
Journal:  Lancet       Date:  2006-03-18       Impact factor: 79.321

7.  A randomized controlled trial of the impact of chlorhexidine skin cleansing on bacterial colonization of hospital-born infants in Nepal.

Authors:  Luke C Mullany; Subarna K Khatry; Jeevan B Sherchand; Steven C LeClerq; Gary L Darmstadt; Joanne Katz; Punita Gauchan; Ramesh K Adhikari; Ashma Rana; James M Tielsch
Journal:  Pediatr Infect Dis J       Date:  2008-06       Impact factor: 2.129

Review 8.  Clinical pharmacokinetics in infants and children. A reappraisal.

Authors:  G L Kearns; M D Reed
Journal:  Clin Pharmacokinet       Date:  1989       Impact factor: 6.447

Review 9.  Umbilical cord antiseptics for preventing sepsis and death among newborns.

Authors:  Aamer Imdad; Resti Ma M Bautista; Kathlynne Anne A Senen; Ma Esterlita V Uy; Jacinto Blas Mantaring; Zulfiqar A Bhutta
Journal:  Cochrane Database Syst Rev       Date:  2013-05-31

10.  Absorption and tolerability of aqueous chlorhexidine gluconate used for skin antisepsis prior to catheter insertion in preterm neonates.

Authors:  A K Chapman; S W Aucott; M M Gilmore; S Advani; W Clarke; A M Milstone
Journal:  J Perinatol       Date:  2013-05-23       Impact factor: 2.521
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