Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 A developmental study of kindling in the rat.

Literature DB >> 7284855

A developmental study of kindling in the rat.

Abstract

Neonate (10 days of age), infant (14 days of age), weanling (21 days of age), juvenile (39 days of age) and adult (over 200 days of age) rats were subjected to repeated electrical stimulation of the amygdala in a kindling paradigm. No differences in the rate or development of the kindling response were observed among adults, juveniles and weanlings. The maximal response to amygdaloid kindling stimulation in neonates and infants was partial and unreliable seizure development. The failure to fully and reliably kindling animals younger than 21 days of age is attributed to immaturity of various mechanisms of neural transmission.

Entities: Disease Species

Mesh：

Year: 1981 PMID： 7284855 DOI： 10.1016/0165-3806(81)90041-9

Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252

Keyword Cloud
Cited

8 in total

1. Developmental emergence of fear learning corresponds with changes in amygdala synaptic plasticity.

Authors: Jason V Thompson; Regina M Sullivan; Donald A Wilson
Journal: Brain Res Date: 2008-02-02 Impact factor: 3.252

2. Corticotropin-releasing hormone-induced seizures in infant rats originate in the amygdala.

Authors: T Z Baram; E Hirsch; O C Snead; L Schultz
Journal: Ann Neurol Date: 1992-05 Impact factor: 10.422

3. Kindling in the early postnatal period: Effects on the dynamics of age-related changes in electrophysiological characteristics of hippocampal neurons.

Authors: I E Kudryashov; T V Pavlova; I V Kudryashova; L K Egorova; N V Gulyaeva
Journal: Neurosci Behav Physiol Date: 2007-10

A developmental study of kindling in the rat.

1. Developmental emergence of fear learning corresponds with changes in amygdala synaptic plasticity.

2. Corticotropin-releasing hormone-induced seizures in infant rats originate in the amygdala.

3. Kindling in the early postnatal period: Effects on the dynamics of age-related changes in electrophysiological characteristics of hippocampal neurons.

4. Short-interval amygdala kindling in neonatal rats.

5. Strain and age affect electroconvulsive seizure testing in rats.

6. Corticotropin-releasing hormone is a rapid and potent convulsant in the infant rat.

7. A new rapid kindling variant for induction of cortical epileptogenesis in freely moving rats.

8. Rapid Amygdala Kindling Causes Motor Seizure and Comorbidity of Anxiety- and Depression-Like Behaviors in Rats.