| Literature DB >> 18083004 |
Kimberly D Statler1, Seth Swank, H Steve White.
Abstract
Electroconvulsive seizure thresholds were compared between adolescent and mature Sprague--Dawley, Wistar, and Fischer rats. All strains had similar hindbrain or forebrain seizure thresholds as adolescents. As adults, hindbrain or forebrain seizure thresholds were highest for Sprague--Dawley and lowest for Fischer rats. Conversely, limbic seizure thresholds during adolescence were highest for Fischer rats. Additional study is needed to better delineate strain and maturational effects on electroconvulsive seizure testing.Entities:
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Year: 2007 PMID: 18083004 PMCID: PMC2271073 DOI: 10.1016/j.eplepsyres.2007.11.001
Source DB: PubMed Journal: Epilepsy Res ISSN: 0920-1211 Impact factor: 3.045