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Literature DB >> 7247372

Myxothiazol, a new antibiotic interfering with respiration.

Abstract

Myxothiazol, a new antibiotic from the myxobacterium Myxococcus fulvus, inhibited the growth of many yeasts and fungi at concentrations between 0.01 and 3 micrograms/ml. It was generally inactive against bacteria. The inhibitory effect was cytostatic. With Candida albicans, Saccharomyces cerevisiae, and Mucor hiemalis, the growth inhibition was neutralized by glucose. Soon after being added to a cell suspension, the compound almost completely blocked oxygen consumption.

Entities: Chemical Species

Mesh：

Substances：

Year: 1981 PMID： 7247372 PMCID： PMC181466 DOI： 10.1128/AAC.19.4.504

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

6 in total

1. Studies on the biological action of antimycin A.

Authors: K AHMAD; H G SCHNEIDER; F M STRONG
Journal: Arch Biochem Date: 1950-09

2. The alternate respiratory pathway of Candida albicans.

Authors: M G Shepherd; C M Chin; P A Sullivan
Journal: Arch Microbiol Date: 1978-01-23 Impact factor: 2.552

3. Mode of action of mucidin, a new antifungal antibiotic produced by the basidiomycete Oudemansiella mucida.

Authors: J Subík; M Behún; P Smigán; V Musílek
Journal: Biochim Biophys Acta Date: 1974-04-22

4. Myxothiazol, an antibiotic from Myxococcus fulvus (myxobacterales). II. structure elucidation.

Authors: W Trowitzsch; G Reifenstahl; V Wray; K Gerth
Journal: J Antibiot (Tokyo) Date: 1980-12 Impact factor: 2.649

5. Myxothiazol, an antibiotic from Myxococcus fulvus (myxobacterales). I. Cultivation, isolation, physico-chemical and biological properties.

Authors: K Gerth; H Irschik; H Reichenbach; W Trowitzsch
Journal: J Antibiot (Tokyo) Date: 1980-12 Impact factor: 2.649

6. Ophiocordin, an antifungal antibiotic of Cordyceps ophioglossoides.

Authors: H Kneifel; W A König; W Loeffler; R Müller
Journal: Arch Microbiol Date: 1977-05-13 Impact factor: 2.552

6 in total

8 in total

Myxothiazol, a new antibiotic interfering with respiration.

1. Studies on the biological action of antimycin A.

2. The alternate respiratory pathway of Candida albicans.

3. Mode of action of mucidin, a new antifungal antibiotic produced by the basidiomycete Oudemansiella mucida.

4. Myxothiazol, an antibiotic from Myxococcus fulvus (myxobacterales). II. structure elucidation.

5. Myxothiazol, an antibiotic from Myxococcus fulvus (myxobacterales). I. Cultivation, isolation, physico-chemical and biological properties.

6. Ophiocordin, an antifungal antibiotic of Cordyceps ophioglossoides.

1. Microbial removal of atmospheric carbon tetrachloride in bulk aerobic soils.

Review 2. Cytochrome bc1 complexes of microorganisms.

3. Genetic analysis of desiccation tolerance in Sachharomyces cerevisiae.

4. Autocides produced by Myxococcus xanthus.

5. Mitochondrial and nuclear myxothiazol resistance in Saccharomyces cerevisiae.

Review 6. Antimicrobial peptides from marine proteobacteria.

7. Oxidative stress generated during monensin treatment contributes to altered Toxoplasma gondii mitochondrial function.

Review 8. Bioenergetics of Mycobacterium: An Emerging Landscape for Drug Discovery.