Literature DB >> 7271921

Myxothiazol, an antibiotic from Myxococcus fulvus (myxobacterales). II. structure elucidation.

W Trowitzsch, G Reifenstahl, V Wray, K Gerth.   

Abstract

Myxothiazol is shown to be 4-(6-carbamoyl-3,5-dimethoxy-4-methylhexa-1E,5E-dienyl)-2'-(1,6-dimethylhepta-2 E,4E-dienyl)-2,4'-bithiazole by spectroscopic (mainly 1H NMR, 15C NMR and mass spectroscopic) and chemical methods.

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Year:  1980        PMID： 7271921     DOI： 10.7164/antibiotics.33.1480

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  8 in total

1.  Proton translocation by cytochrome oxidase in (antimycin + myxothiazol)-treated rat liver mitochondria using ferrocyanide or hexammineruthenium as electron donor.

Authors:  I C West; R Mitchell; A J Moody; P Mitchell
Journal:  Biochem J       Date:  1986-05-15       Impact factor: 3.857

2.  Posttranslational modifications in microcin B17 define an additional class of DNA gyrase inhibitor.

Authors:  P Yorgey; J Lee; J Kördel; E Vivas; P Warner; D Jebaratnam; R Kolter
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-10       Impact factor: 11.205

3.  Myxothiazol, a new antibiotic interfering with respiration.

Authors:  G Thierbach; H Reichenbach
Journal:  Antimicrob Agents Chemother       Date:  1981-04       Impact factor: 5.191

4.  Mitochondrial and nuclear myxothiazol resistance in Saccharomyces cerevisiae.

Authors:  G Thierbach; G Michaelis
Journal:  Mol Gen Genet       Date:  1982

5.  Self-resistance guided genome mining uncovers new topoisomerase inhibitors from myxobacteria.

Authors:  Fabian Panter; Daniel Krug; Sascha Baumann; Rolf Müller
Journal:  Chem Sci       Date:  2018-05-03       Impact factor: 9.825

6.  Investigations into the biosynthesis of the antifungal strobilurins.

Authors:  Zafar Iqbal; Li-Chen Han; Anna M Soares-Sello; Risa Nofiani; Gerald Thormann; Axel Zeeck; Russell J Cox; Christine L Willis; Thomas J Simpson
Journal:  Org Biomol Chem       Date:  2018-08-01       Impact factor: 3.876

7.  Reconstitution of the myxothiazol biosynthetic gene cluster by Red/ET recombination and heterologous expression in Myxococcus xanthus.

Authors:  Olena Perlova; Jun Fu; Silvia Kuhlmann; Daniel Krug; A Francis Stewart; Youming Zhang; Rolf Müller
Journal:  Appl Environ Microbiol       Date:  2006-09-22       Impact factor: 4.792

Review 8.  Antimicrobial peptides from marine proteobacteria.

Authors:  Florie Desriac; Camille Jégou; Eric Balnois; Benjamin Brillet; Patrick Le Chevalier; Yannick Fleury
Journal:  Mar Drugs       Date:  2013-09-30       Impact factor: 5.118
  8 in total

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