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Literature DB >> 6788741

Myxothiazol, an antibiotic from Myxococcus fulvus (myxobacterales). I. Cultivation, isolation, physico-chemical and biological properties.

K Gerth, H Irschik, H Reichenbach, W Trowitzsch.

Abstract

Myxothiazol (AB-Mx f16-1), a new antifungal antibiotic, is produced by the myxobacterium Myxococcus fulvus strain Mx f16. It is active against many filamentous fungi, and completely inhibits growth of Mucor hiemalis at a concentration of 2 micrograms/ml. The molecular formula of myxothiazol was determined to e C25H33N3O3S2.

Entities: Chemical Species

Mesh：

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Year: 1980 PMID： 6788741 DOI： 10.7164/antibiotics.33.1474

Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649

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Cited

18 in total

Review 1. Cytochrome bc1 complexes of microorganisms.

Authors: B L Trumpower
Journal: Microbiol Rev Date: 1990-06

2. Steady-state kinetics of the overall oxidative phosphorylation reaction in heart mitochondria. Determination of the coupling relationships between the respiratory reactions and miscellaneous observations concerning rate-limiting steps.

Authors: C D Stoner
Journal: J Bioenerg Biomembr Date: 1984-04 Impact factor: 2.945

3. Mycobacterial Membrane Proteins QcrB and AtpE: Roles in Energetics, Antibiotic Targets, and Associated Mechanisms of Resistance.

Authors: Luke Bown; Santosh K Srivastava; Brandon M Piercey; Clarissa K McIsaac; Kapil Tahlan
Journal: J Membr Biol Date: 2017-11-02 Impact factor: 1.843

4. Catalytic Reactions and Energy Conservation in the Cytochrome bc₁ and b₆f Complexes of Energy-Transducing Membranes.

Authors: Marcin Sarewicz; Sebastian Pintscher; Rafał Pietras; Arkadiusz Borek; Łukasz Bujnowicz; Guy Hanke; William A Cramer; Giovanni Finazzi; Artur Osyczka
Journal: Chem Rev Date: 2021-01-19 Impact factor: 60.622

5. The effect of respiratory chain impairment of beta-oxidation in rat heart mitochondria.

Authors: S Eaton; M Pourfarzam; K Bartlett
Journal: Biochem J Date: 1996-10-15 Impact factor: 3.857

6. Combining Inhibitor Resistance-conferring Mutations in Cytochrome b Creates Conditional Synthetic Lethality in Saccharomyces cerevisiae.

Authors: Martina G Ding; Jean-Paul di Rago; Bernard L Trumpower
Journal: J Biol Chem Date: 2009-01-29 Impact factor: 5.157

Myxothiazol, an antibiotic from Myxococcus fulvus (myxobacterales). I. Cultivation, isolation, physico-chemical and biological properties.

Review 1. Cytochrome bc1 complexes of microorganisms.

2. Steady-state kinetics of the overall oxidative phosphorylation reaction in heart mitochondria. Determination of the coupling relationships between the respiratory reactions and miscellaneous observations concerning rate-limiting steps.

3. Mycobacterial Membrane Proteins QcrB and AtpE: Roles in Energetics, Antibiotic Targets, and Associated Mechanisms of Resistance.

4. Catalytic Reactions and Energy Conservation in the Cytochrome bc₁ and b₆f Complexes of Energy-Transducing Membranes.

5. The effect of respiratory chain impairment of beta-oxidation in rat heart mitochondria.

6. Combining Inhibitor Resistance-conferring Mutations in Cytochrome b Creates Conditional Synthetic Lethality in Saccharomyces cerevisiae.

7. Myxothiazol, a new antibiotic interfering with respiration.

8. Mitochondrial and nuclear myxothiazol resistance in Saccharomyces cerevisiae.

9. Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.

10. Oxidative capacity interacts with oxygen delivery to determine maximal O(2) uptake in rat skeletal muscles in situ.