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Literature DB >> 7242271

Chaulmoogric acid: assimilation into the complex lipids of mycobacteria.

Abstract

Lipid analysis of Mycobacterium vaccae, grown in the presence of chaulmoogric acid, demonstrates that this cyclopentenyl fatty acid is taken up by the organism and incorporated into cellular phospholipids and triacylglycerols. As cell growth is retarded by the addition of chaulmoogric acid to the growth medium, it is possible that the antimicrobial properties of this compound results from a perturbation of membrane processes.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1981 PMID： 7242271 DOI： 10.1007/bf02535690

Source DB: PubMed Journal: Lipids ISSN： 0024-4201 Impact factor: 1.880

16 in total

Review 1. Physical properties of membrane lipids: biological relevance and regulation.

Authors: J E Cronan; E P Gelmann
Journal: Bacteriol Rev Date: 1975-09

2. Modification of glycerolipid metabolism in L-M fibroblasts by an unnatural amino-alcohol, N-isopropylethanolamine.

Authors: M L Blank; C Piantadosi; K S Ishaq; F Snyder
Journal: Biochem Biophys Res Commun Date: 1975-02-17 Impact factor: 3.575

3. Alteration of fatty acid composition of LM cells by lipid supplementation and temperature.

Authors: K A Ferguson; M Glaser; W H Bayer; P R Vagelos
Journal: Biochemistry Date: 1975-01-14 Impact factor: 3.162

4. The effect of alterations in fatty acid composition and cholesterol content on the nonelectrolyte permeability of Acholeplasma laidlawii B cells and derived liposomes.

Authors: R N Mcelhaney; J de Gier; E C van der Neut-Kok
Journal: Biochim Biophys Acta Date: 1973-03-16

5. The manipulation of fatty acid composition in L-M cell monolayers supplemented with cyclopentenyl fatty acids.

Authors: M C Cabot; F Snyder
Journal: Arch Biochem Biophys Date: 1978-10 Impact factor: 4.013

6. Isolation and characterization of subcellular membranes with altered phospholipid composition from cultured fibroblasts.

Authors: F Schroeder; J F Perlmutter; M Glaser; P R Vagelos
Journal: J Biol Chem Date: 1976-08-25 Impact factor: 5.157

7. A shift from phospholipid to triglyceride synthesis when cell division is inhibited by trans-fatty acids.

Authors: G Graff; W E Lands
Journal: Chem Phys Lipids Date: 1976-10 Impact factor: 3.329

8. Manipulation of fatty acid composition in animal cells grown in culture.

Authors: B J Wisnieski; R E Williams; C F Fox
Journal: Proc Natl Acad Sci U S A Date: 1973-12 Impact factor: 11.205

9. Effect of oleic acid on growth and cell structure of mycobacteria.

Authors: W B Schaefer; C W Lewis
Journal: J Bacteriol Date: 1965-11 Impact factor: 3.490

10. Biosynthesis of cyclopentenyl fatty acids. Cyclopentenylglycine, a non-proteinogenic amino acid as precursor of cyclic fatty acids in Flacourtiaceae.

Authors: U Cramer; F Spener
Journal: Eur J Biochem Date: 1977-04-15

4 in total