Literature DB >> 791526

A shift from phospholipid to triglyceride synthesis when cell division is inhibited by trans-fatty acids.

G Graff, W E Lands.   

Abstract

The yeast mutant Saccharomyces cerevisiae (KD 46) requires added unsaturated fatty acid for growth. When cell growth was inhibited by the presence of trans-acids there was a marked inhibition of oleate esterification into phospholipids accompanying continued incorporation into triglycerides. Apparently some control point in phospholipid synthesis associated with the cell cycle occurs after the stage of phosphatidate biosynthesis.

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Year:  1976        PMID: 791526     DOI: 10.1016/0009-3084(76)90075-x

Source DB:  PubMed          Journal:  Chem Phys Lipids        ISSN: 0009-3084            Impact factor:   3.329


  3 in total

Review 1.  Learning how membrane fatty acids affect cardiovascular integrity.

Authors:  William E M Lands
Journal:  J Membr Biol       Date:  2005-07       Impact factor: 1.843

2.  Chaulmoogric acid: assimilation into the complex lipids of mycobacteria.

Authors:  M C Cabot; C R Goucher
Journal:  Lipids       Date:  1981-02       Impact factor: 1.880

3.  Effects of unsaturated fatty acid deprivation on neutral lipid synthesis in Saccharomyces cerevisiae.

Authors:  T M Buttke; A L Pyle
Journal:  J Bacteriol       Date:  1982-11       Impact factor: 3.490

  3 in total

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