Literature DB >> 7240352

The GENE-TOX program: genetic activity evaluation.

M D Waters, A Auletta.   

Abstract

The GENE-TOX program, a two-phase evaluation from the existing literature of selected bioassays for detecting mutagenicity and presumptive carcinogenicity, is described. Sponsored and directed by the Office of Testing and Evaluation within the U.S. Environmental Protection Agency's (EPA) Office of Pesticides and Toxic Substances, this program will aid EPA in establishing standard genetic testing and evaluation procedures for the regulation of toxic substances and determining the direction of research and development in the area of genetic toxicology.

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Year:  1981        PMID： 7240352     DOI： 10.1021/ci00029a007

Source DB:  PubMed          Journal:  J Chem Inf Comput Sci        ISSN： 0095-2338


  10 in total

Review 1.  Genetic toxicology in the 21st century: reflections and future directions.

Authors:  Brinda Mahadevan; Ronald D Snyder; Michael D Waters; R Daniel Benz; Raymond A Kemper; Raymond R Tice; Ann M Richard
Journal:  Environ Mol Mutagen       Date:  2011-04-28       Impact factor: 3.216

2.  1986 survey of genetic toxicology testing in industry, government contract, and academic laboratories.

Authors:  A E Auletta; M G Farrow
Journal:  Cell Biol Toxicol       Date:  1991-07       Impact factor: 6.691

Review 3.  The Salmonella mutagenicity assay: the stethoscope of genetic toxicology for the 21st century.

Authors:  Larry D Claxton; Gisela de A Umbuzeiro; David M DeMarini
Journal:  Environ Health Perspect       Date:  2010-11       Impact factor: 9.031

Review 4.  The mutagenesis moonshot: The propitious beginnings of the environmental mutagenesis and genomics society.

Authors:  David M DeMarini
Journal:  Environ Mol Mutagen       Date:  2019-08-06       Impact factor: 3.579

5.  Comparative evaluation of genetic toxicity patterns of carcinogens and noncarcinogens: strategies for predictive use of short-term assays.

Authors:  R W Tennant; J W Spalding; S Stasiewicz; W D Caspary; J M Mason; M A Resnick
Journal:  Environ Health Perspect       Date:  1987-11       Impact factor: 9.031

6.  The Genetic Activity Profile database.

Authors:  M D Waters; H F Stack; N E Garrett; M A Jackson
Journal:  Environ Health Perspect       Date:  1991-12       Impact factor: 9.031

Review 7.  Computer-assisted studies of molecular structure and genotoxic activity by pattern recognition techniques.

Authors:  T R Stouch; P C Jurs
Journal:  Environ Health Perspect       Date:  1985-09       Impact factor: 9.031

8.  Hazard identification: efficiency of short-term tests in identifying germ cell mutagens and putative nongenotoxic carcinogens.

Authors:  M D Waters; H F Stack; M A Jackson; B A Bridges
Journal:  Environ Health Perspect       Date:  1993-10       Impact factor: 9.031

9.  Mode of action and the assessment of chemical hazards in the presence of limited data: use of structure-activity relationships (SAR) under TSCA, Section 5.

Authors:  C M Auer; J V Nabholz; K P Baetcke
Journal:  Environ Health Perspect       Date:  1990-07       Impact factor: 9.031

10.  Use of selected toxicology information resources in assessing relationships between chemical structure and biological activity.

Authors:  J S Wassom
Journal:  Environ Health Perspect       Date:  1985-09       Impact factor: 9.031
  10 in total

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