Literature DB >> 7215378

A mathematical model for the liver uptake and excretion of 99mTc-diethyl IDA.

L Gelius, A Skretting, M Aas.   

Abstract

A mathematical model for the liver uptake and excretion of 99mTc-diethyl IDA has been formulated and data from four patient studies have been fitted to the model, resulting in values for the model parameters. The model includes compartments for blood, extravascular space, hepatocytes, bile ducts, and kidneys. The parameter values obtained reflect a rapid exchange between blood and extravascular space and a significant reverse flow of the radiopharmaceutical from the liver to the blood.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 7215378     DOI： 10.1007/bf00253161

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  5 in total

1.  Some formal approaches to the analysis of kinetic data in terms of linear compartmental systems.

Authors:  M BERMAN; M F WEISS; E SHAHN
Journal:  Biophys J       Date:  1962-05       Impact factor: 4.033

2.  Quantitative measurement of liver function with radioactive rose bengal.

Authors:  M DORLEYN; J COENEGRACHT
Journal:  Medicamundi       Date:  1959

3.  Technetium-99m-labeled n-(2,6-dimethylphenylcarbamoylmethyl) iminodiacetic acid (tc-99m HIDA): a new radiopharmaceutical for hepatobiliary imaging studies.

Authors:  J Ryan; M Cooper; M Loberg; E Harvey; S Sikorski
Journal:  J Nucl Med       Date:  1977-10       Impact factor: 10.057

4.  An evaluation of 99mTc-labeled hepatobiliary agents.

Authors:  B W Wistow; G Subramanian; R L Heertum; R W Henderson; G M Gagne; R C Hall; J G McAfee
Journal:  J Nucl Med       Date:  1977-05       Impact factor: 10.057

5.  The kinetics of 131-I labelled rose bengal in the differential diagnosis of cholestasis studied by compartmental analysis and digital computing techniques.

Authors:  G L Turco; F Ghemi; P De Flippi; G Segre
Journal:  J Nucl Biol Med       Date:  1968 Apr-Jun
  5 in total
  4 in total

1.  Measurement of hepatic blood flow with diethyl-Ida in man. Comparison with indocyanine green.

Authors:  C Muńoz; L Blanchet; D Lebrec
Journal:  Eur J Nucl Med       Date:  1982

2.  A practical approach to the hepatobiliary kinetics of 99mTc-HIDA. Clinical validation of the method and a preliminary report on its use for parametric imaging.

Authors:  G Galli; C L Maini; M Salvatori; F Andreasi
Journal:  Eur J Nucl Med       Date:  1983

3.  The influence of bilirubin, alcohol and certain drugs on the kinetics of 99mTc-Diethyl IDA (EHIDA) in humans.

Authors:  J M Coenegracht; T L Oei; P J van Breda Vriesman
Journal:  Eur J Nucl Med       Date:  1983

4.  99mTc-diethyl-IDA: the extraction efficiency of the liver.

Authors:  G Galli; P Orlando; P Massari; N Bonifazi; P Magistrelli; R Coppola
Journal:  Eur J Nucl Med       Date:  1983
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.