Literature DB >> 6307697

99mTc-diethyl-IDA: the extraction efficiency of the liver.

G Galli, P Orlando, P Massari, N Bonifazi, P Magistrelli, R Coppola.   

Abstract

The extraction efficiencies of the liver were studied in rabbits by injection in the portal vein of 99mTc-IDA and 131I-Rose Bengal in two experimental conditions. In the first experiment blood samples were collected for one minute from a catheter inserted into the vena cava with the tip at the sovrahepatic veins outflow level. The vena cava was ligated upperstream. In the second experiment blood was collected from the general circulation every other minute for 20' after administration. Control experiments were performed in rabbits by administration of 99mTc-Pertechnetate and 99mTc-Albumin. The results showed that the extraction of diethyl-IDA from the blood flowing through the liver is almost total.

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Year:  1983        PMID： 6307697     DOI： 10.1007/bf00253763

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  7 in total

1.  Estimation of hepatic blood flow in man and in dogs by I 131-labeled rose bengal; simultaneous comparison with sulfobromophthalein sodium.

Authors:  B COMBES
Journal:  J Lab Clin Med       Date:  1960-10

Review 2.  Measurement of hepatic blood flow.

Authors:  J H Christie; T K Chaudhuri
Journal:  Semin Nucl Med       Date:  1972-04       Impact factor: 4.446

3.  A mathematical model for the liver uptake and excretion of 99mTc-diethyl IDA.

Authors:  L Gelius; A Skretting; M Aas
Journal:  Eur J Nucl Med       Date:  1981-04

4.  Hepatic clearance mechanism of Tc-99m-HIDA and its effect on quantitation of hepatobiliary function: Concise communication.

Authors:  E Harvey; M Loberg; J Ryan; S Sikorski; W Faith; M Cooper
Journal:  J Nucl Med       Date:  1979-04       Impact factor: 10.057

5.  Heterogeneous intrahepatic distribution of blood flow in humans.

Authors:  T Kashiwagi; K Kimura; T Suematsu; M Schichiri; T Kamada; H Abe
Journal:  Eur J Nucl Med       Date:  1981-12

Review 6.  Radiopharmaceuticals for hepatobiliary imaging.

Authors:  L R Chervu; A D Nunn; M D Loberg
Journal:  Semin Nucl Med       Date:  1982-01       Impact factor: 4.446

7.  Comparative quantitative evaluation of hepatic clearance of diethyl-IDA and para-butyl-IDA in jaundiced and non-jaundiced patients.

Authors:  G L Tarolo; R Picozzi; B Palagi; F Cammelli
Journal:  Eur J Nucl Med       Date:  1981-12
  7 in total
  1 in total

Review 1.  Model identification and estimation of organ-function parameters using radioactive tracers and the impulse-response function.

Authors:  Z Szabó; H Vosberg; C A Sondhaus; L E Feinendegen
Journal:  Eur J Nucl Med       Date:  1985
  1 in total

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