Literature DB >> 7208593

Anesthetic, hypothermic, myorelaxant and anticonvulsant effects of synthetic eugenol derivatives and natural analogues.

K Dallmeier, E A Carlini.   

Abstract

Nine newly synthesized eugenol derivatives were investigated in rats or mice as to their anesthetic, hypothermic, myorelaxant and anticonvulsant effects. Additional pharmacological activity which appeared during the experiments is described. For comparative purposes, six naturally occurring eugenol analogues were included in the study. The results are further discussed as to possible structure-activity relationships between the test compounds and the four investigated effects.

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Year:  1981        PMID： 7208593     DOI： 10.1159/000137479

Source DB:  PubMed          Journal:  Pharmacology        ISSN： 0031-7012            Impact factor:   2.547


  16 in total

1.  Characterizing the effects of Eugenol on neuronal ionic currents and hyperexcitability.

Authors:  Chin-Wei Huang; Julie Chi Chow; Jing-Jane Tsai; Sheng-Nan Wu
Journal:  Psychopharmacology (Berl)       Date:  2011-12-13       Impact factor: 4.530

Review 2.  Biological Activities of Essential Oils: From Plant Chemoecology to Traditional Healing Systems.

Authors:  Javad Sharifi-Rad; Antoni Sureda; Gian Carlo Tenore; Maria Daglia; Mehdi Sharifi-Rad; Marco Valussi; Rosa Tundis; Marzieh Sharifi-Rad; Monica R Loizzo; Adedayo Oluwaseun Ademiluyi; Razieh Sharifi-Rad; Seyed Abdulmajid Ayatollahi; Marcello Iriti
Journal:  Molecules       Date:  2017-01-01       Impact factor: 4.411

Review 3.  Perspectives on medicinal properties of natural phenolic monoterpenoids and their hybrids.

Authors:  Jamatsing D Rajput; Suresh D Bagul; Umesh D Pete; Chetan M Zade; Subhash B Padhye; Ratnamala S Bendre
Journal:  Mol Divers       Date:  2017-10-07       Impact factor: 2.943

4.  Biological effects of Ocimum gratissimum L. are due to synergic action among multiple compounds present in essential oil.

Authors:  Luciane Almeida Galindo; Aline de Moraes Pultrini; Mirtes Costa
Journal:  J Nat Med       Date:  2010-06-18       Impact factor: 2.343

5.  Inhibition of Nav1.7 channels by methyl eugenol as a mechanism underlying its antinociceptive and anesthetic actions.

Authors:  Ze-Jun Wang; Boris Tabakoff; Simon R Levinson; Thomas Heinbockel
Journal:  Acta Pharmacol Sin       Date:  2015-06-08       Impact factor: 6.150

6.  Clove cigarettes. The basis for concern regarding health effects.

Authors:  T L Guidotti; L Laing; U B Prakash
Journal:  West J Med       Date:  1989-08

7.  Central Nervous System Effects of Iso-6-spectaline Isolated from Senna Spectabilis var. Excelsa (Schrad) in Mice.

Authors:  Fo Silva; Mgv Silva; Gs Cerqueira; Eb Sabino; Aac Almeida; Jp Costa; Rm Freitas
Journal:  J Young Pharm       Date:  2011-07

8.  Evaluation of Antiseizure Activity of Essential Oil from Roots of Angelica archangelica Linn. in Mice.

Authors:  Shalini Pathak; M M Wanjari; S K Jain; M Tripathi
Journal:  Indian J Pharm Sci       Date:  2010-05       Impact factor: 0.975

9.  Anticonvulsant and anxiolytic evaluation of leaf extracts of Ocimum gratissimum, a culinary herb.

Authors:  C O Okoli; A C Ezike; O C Agwagah; P A Akah
Journal:  Pharmacognosy Res       Date:  2010-01

10.  Analgesic effect of the aqueous and ethanolic extracts of clove.

Authors:  Mina Kamkar Asl; Ashraf Nazariborun; Mahmoud Hosseini
Journal:  Avicenna J Phytomed       Date:  2013
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