Literature DB >> 28988386

Perspectives on medicinal properties of natural phenolic monoterpenoids and their hybrids.

Jamatsing D Rajput1, Suresh D Bagul1, Umesh D Pete1, Chetan M Zade1, Subhash B Padhye2,3, Ratnamala S Bendre4.   

Abstract

Carvacrol, thymol and eugenol belong to a class of naturally presenting phenols with a ten-carbon unit, which are present in essential oils of many plants. These versatile molecules are incorporated as useful ingredients in many food products and find applications in agricultural, pharmaceutical, fragrance, cosmetic, flavor and other industries. They are wide ranging of biological and pharmaceutical activities: anti-inflammatory, antimicrobial, analgesic, anticancer and antioxidant. This review summarizes pharmacological and medicinal activities of these phytochemicals and their synthetic hybrids.

Entities:  

Keywords:  Carvacrol; Essential oils; Eugenol; Pharmacological and medicinal activities; Thymol

Mesh：

Substances：

Year:  2017        PMID： 28988386     DOI： 10.1007/s11030-017-9787-y

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  37 in total

1.  Drug design via pharmacophore identification. Dopaminergic activity of 3H-benz[e]indol-8-amines and their mode of interaction with the dopamine receptor.

Authors:  A A Asselin; L G Humber; K Voith; G Metcalf
Journal:  J Med Chem       Date:  1986-05       Impact factor: 7.446

2.  Carvacrol attenuates mechanical hypernociception and inflammatory response.

Authors:  Adriana G Guimarães; Maria A Xavier; Marília T de Santana; Enilton A Camargo; Cliomar A Santos; Fabíola A Brito; Emiliano O Barreto; Sócrates C H Cavalcanti; Angelo R Antoniolli; Rita C M Oliveira; Lucindo J Quintans-Júnior
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2011-12-03       Impact factor: 3.000

3.  Fluorescent Human EP3 Receptor Antagonists.

Authors:  Miriam Tomasch; J Stephan Schwed; Karina Kuczka; Sascha Meyer Dos Santos; Sebastian Harder; Rolf M Nüsing; Alexander Paulke; Holger Stark
Journal:  ACS Med Chem Lett       Date:  2012-08-08       Impact factor: 4.345

4.  Identification and structure-activity relationship study of carvacrol derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors.

Authors:  Reshma Alokam; Variam Ullas Jeankumar; Jonnalagadda Padma Sridevi; Siddharth Sai Matikonda; Santosh Peddi; Mallika Alvala; Perumal Yogeeswari; Dharmarajan Sriram
Journal:  J Enzyme Inhib Med Chem       Date:  2013-10-03       Impact factor: 5.051

5.  Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa.

Authors:  Tamara L Meragelman; Dominic A Scudiero; R Eric Davis; Louis M Staudt; Thomas G McCloud; John H Cardellina; Robert H Shoemaker
Journal:  J Nat Prod       Date:  2009-03-27       Impact factor: 4.050

Review 6.  Biologic properties of eugenol and zinc oxide-eugenol. A clinically oriented review.

Authors:  K Markowitz; M Moynihan; M Liu; S Kim
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1992-06

7.  Migration study of carvacrol as a natural antioxidant in high-density polyethylene for active packaging.

Authors:  M Peltzer; J Wagner; A Jimenez
Journal:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess       Date:  2009-06

8.  Effects of terpenoid phenol derivatives on calcium current in canine and human ventricular cardiomyocytes.

Authors:  János Magyar; Norbert Szentandrássy; Tamás Bányász; László Fülöp; András Varró; Péter P Nánási
Journal:  Eur J Pharmacol       Date:  2004-03-08       Impact factor: 4.432

9.  Screening chemical composition and in vitro antioxidant and antimicrobial activities of the essential oils from Origanum syriacum L. growing in Turkey.

Authors:  Mehmet Hakki Alma; Ahmet Mavi; Ali Yildirim; Metin Digrak; Toshifumi Hirata
Journal:  Biol Pharm Bull       Date:  2003-12       Impact factor: 2.233

10.  Antifungal activity of eugenol analogues. Influence of different substituents and studies on mechanism of action.

Authors:  Héctor Carrasco; Marcela Raimondi; Laura Svetaz; Melina Di Liberto; María V Rodriguez; Luis Espinoza; Alejandro Madrid; Susana Zacchino
Journal:  Molecules       Date:  2012-01-19       Impact factor: 4.411
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  5 in total

1.  Insect growth regulatory activity of carvacrol-based 1,3,4-thiadiazoles and 1,3,4-oxadiazoles.

Authors:  Suresh D Bagul; Jamatsing D Rajput; Chitra Srivastava; Ratnamala S Bendre
Journal:  Mol Divers       Date:  2018-03-23       Impact factor: 2.943

2.  Morita-Baylis-Hillman adducts derived from thymol: synthesis, in silico studies and biological activity against Giardia lamblia.

Authors:  Francisco J S Xavier; Andressa B Lira; Gabriel C Verissimo; Fernanda S de S Saraiva; Abrahão A de Oliveira Filho; Elaine M de Souza-Fagundes; Margareth de F F M Diniz; Maria A Gomes; Aleff C Castro; Fábio P L Silva; Claudio G Lima-Junior; Mário L A A Vasconcellos
Journal:  Mol Divers       Date:  2021-09-05       Impact factor: 3.364

Review 3.  An Overview on the Anti-inflammatory Potential and Antioxidant Profile of Eugenol.

Authors:  Joice Nascimento Barboza; Carlos da Silva Maia Bezerra Filho; Renan Oliveira Silva; Jand Venes R Medeiros; Damião Pergentino de Sousa
Journal:  Oxid Med Cell Longev       Date:  2018-10-22       Impact factor: 6.543

4.  Functional Characterization and Structural Insights Into Stereoselectivity of Pulegone Reductase in Menthol Biosynthesis.

Authors:  Chanchan Liu; Qiyu Gao; Zhuo Shang; Jian Liu; Siwei Zhou; Jingjie Dang; Licheng Liu; Iris Lange; Narayanan Srividya; B Markus Lange; Qinan Wu; Wei Lin
Journal:  Front Plant Sci       Date:  2021-11-30       Impact factor: 5.753

Review 5.  Tailored Functionalization of Natural Phenols to Improve Biological Activity.

Authors:  Barbara Floris; Pierluca Galloni; Valeria Conte; Federica Sabuzi
Journal:  Biomolecules       Date:  2021-09-07
  5 in total

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