Literature DB >> 7201775

Attempted tumor induction with agaritine in mice.

B Toth, C R Raha, L Wallcave, D Nagel.   

Abstract

Agaritine, a constituent of the cultivated mushroom of commerce Agaricus bisporus, was administered at concentrations of 0.0625 and 0.03125% in drinking water daily for life to randomly bred Swiss mice. Consumption of the chemical resulted in no detectable carcinogenic action under the experimental conditions. During the course of the experiment, however, a substantial number of animals developed convulsive seizures.

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Year:  1981        PMID： 7201775

Source DB:  PubMed          Journal:  Anticancer Res        ISSN： 0250-7005            Impact factor:   2.480


  7 in total

1.  Mutagenic and genotoxic activities of extracts derived from the cooked and raw edible mushroom Agaricus bisporus.

Authors:  B L Pool-Zobel; P Schmezer; Y Sinrachatanant; F Kaleagasioglu; K Reinhart; R Martin; P Klein; A R Tricker
Journal:  J Cancer Res Clin Oncol       Date:  1990       Impact factor: 4.553

2.  Lack of carcinogenicity of agaritine by subcutaneous administration in mice.

Authors:  B Toth; H Sornson
Journal:  Mycopathologia       Date:  1984-03-15       Impact factor: 2.574

3.  Agaricus bisporus: an assessment of its carcinogenic potency.

Authors:  B Toth; P Gannett
Journal:  Mycopathologia       Date:  1993-11       Impact factor: 2.574

4.  Phase I Clinical Study of the Dietary Supplement, Agaricus blazei Murill, in Cancer Patients in Remission.

Authors:  Satoshi Ohno; Yoshiteru Sumiyoshi; Katsuyoshi Hashine; Akitomi Shirato; Satoru Kyo; Masaki Inoue
Journal:  Evid Based Complement Alternat Med       Date:  2011-04-18       Impact factor: 2.629

5.  The Medicinal Mushroom Agaricus blazei Murrill: Review of Literature and Pharmaco-Toxicological Problems.

Authors:  F Firenzuoli; L Gori; G Lombardo
Journal:  Evid Based Complement Alternat Med       Date:  2008-03       Impact factor: 2.629

Review 6.  Chronological supplement to the Carcinogenic Potency Database: standardized results of animal bioassays published through December 1982.

Authors:  L S Gold; M de Veciana; G M Backman; R Magaw; P Lopipero; M Smith; M Blumenthal; R Levinson; L Bernstein; B N Ames
Journal:  Environ Health Perspect       Date:  1986-08       Impact factor: 9.031

7.  Gastric tumorigenesis by a single dose of 4-(hydroxymethyl)benzenediazonium ion of Agaricus bisporus.

Authors:  B Toth; D Nagel; A Ross
Journal:  Br J Cancer       Date:  1982-09       Impact factor: 7.640
  7 in total

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