Literature DB >> 8008044

Agaricus bisporus: an assessment of its carcinogenic potency.

B Toth1, P Gannett.   

Abstract

This assessment focuses on the concentrations of some chemicals present in the Agaricus bisporus mushroom, the cancer-inducing doses of these chemicals or mushroom used in the animal experiments, the total amounts of these chemicals or mushroom needed to induce cancer in these mice, and the estimated total amounts of these chemicals or mushroom needed to induce cancer in humans. By adding the estimated amounts of chemicals needed to induce cancer and by comparing it with the amount of raw mushroom needed to induce the same effect, it becomes obvious that we have accounted for less than 2% of the carcinogenic components of the Agaricus bisporus mushroom. Since some unavailable data handicapped this assessment, it should be regarded as tentative and subject to further adjustment.

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Year:  1993        PMID: 8008044     DOI: 10.1007/BF01103105

Source DB:  PubMed          Journal:  Mycopathologia        ISSN: 0301-486X            Impact factor:   2.574


  17 in total

Review 1.  Naturally occurring compounds Containing a nitrogen-nitrogen bond.

Authors:  T A LaRue
Journal:  Lloydia       Date:  1977 Jul-Aug

2.  Carcinogenesis of 4-(hydroxymethyl)benzenediazonium ion (tetrafluoroborate) of Agaricus bisporus.

Authors:  B Toth; K Patil; H S Jae
Journal:  Cancer Res       Date:  1981-06       Impact factor: 12.701

3.  Aortic rupture and aortic smooth muscle tumors in mice. Induction by p-hydrazinobenzoic acid hydrochloride of the cultivated mushroom Agaricus bisporus.

Authors:  B M McManus; B Toth; K D Patil
Journal:  Lab Invest       Date:  1987-07       Impact factor: 5.662

4.  Cancer induction in mice by feeding of the uncooked cultivated mushroom of commerce Agaricus bisporus.

Authors:  B Toth; J Erickson
Journal:  Cancer Res       Date:  1986-08       Impact factor: 12.701

5.  [Rapid determination of agaritin in commercial mushrooms (Agaricus bisporus) with high performance liquid chromatography].

Authors:  B Fischer; J Lüthy; C Schlatter
Journal:  Z Lebensm Unters Forsch       Date:  1984-09

6.  Carcinogenesis by N2-[gamma-L(+)-glutamyl]-4-carboxyphenylhydrazine of Agaricus bisporus in mice.

Authors:  B Toth
Journal:  Anticancer Res       Date:  1986 Sep-Oct       Impact factor: 2.480

7.  Occurrence, stability and decomposition of beta-N [gamma-L(+)-glutamyl]-4-hydroxymethylphenylhydrazine (agaritine) from the mushroom Agaricus bisporus.

Authors:  A E Ross; D L Nagel; B Toth
Journal:  Food Chem Toxicol       Date:  1982-12       Impact factor: 6.023

8.  Tumor induction with the N'-acetyl derivative of 4-hydroxymethyl-phenylhydrazine, a metabolite of agaritine of Agaricus bisporus.

Authors:  B Toth; D Nagel; K Patil; J Erickson; K Antonson
Journal:  Cancer Res       Date:  1978-01       Impact factor: 12.701

9.  An aromatic diazonium compound in the mushroom Agaricus bisporus.

Authors:  B LEVENBERG
Journal:  Biochim Biophys Acta       Date:  1962-09-10

10.  Gastric tumorigenesis by a single dose of 4-(hydroxymethyl)benzenediazonium ion of Agaricus bisporus.

Authors:  B Toth; D Nagel; A Ross
Journal:  Br J Cancer       Date:  1982-09       Impact factor: 7.640

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