Literature DB >> 7195349

Effect of acute and chronic ethanol ingestion on the content of reduced glutathione of various tissues of the rat.

V Fernández, L A Videla.   

Abstract

The effect of acute ethanol ingestion (5 g/kg) by fasted rats, or chronic treatment in fed animals, revealed a significant decrease in the content of reduced glutathione of the liver and kidney. No changes were observed in reduced glutathione levels of the pancreas, stomach or spleen in the acute model. In this condition, the time course study of the decrease in reduced glutathione levels showed a progressive effect in the liver and a rapid and constant effect in the kidney.

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Year:  1981        PMID： 7195349     DOI： 10.1007/bf01959881

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  19 in total

Review 1.  Liver hypermetabolic state after chronic ethanol consumption: hormonal interrelations and pathogenic implications.

Authors:  Y Israel; L Videla; J Bernstein
Journal:  Fed Proc       Date:  1975-10

2.  Lipid peroxidation in isolated hepatocytes from rats ingesting ethanol chronically.

Authors:  H Remmer; D Albrecht; H Kappus
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-06       Impact factor: 3.000

3.  Increased biliary glutathione disulfide release in chronically ethanol-treated rats.

Authors:  H Sies; O R Koch; E Martino; A Boveris
Journal:  FEBS Lett       Date:  1979-07-15       Impact factor: 4.124

4.  A correlation between glutathione levels and cellular damage in isolated hepatocytes.

Authors:  J Högberg; A Kristoferson
Journal:  Eur J Biochem       Date:  1977-03-15

5.  Effect of acute ethanol ingestion on lipoperoxidation and on the activity of the enzymes related to peroxide metabolism in rat liver.

Authors:  A Valenzuela; N Fernandez; V Fernandez; G Ugarte; L A Videla
Journal:  FEBS Lett       Date:  1980-02-25       Impact factor: 4.124

6.  Effect of acute ethanol intoxication on the content of reduced glutathione of the liver in relation to its lipoperoxidative capacity in the rat.

Authors:  L A Videla; V Fernandez; G Ugarte; A Valenzuela
Journal:  FEBS Lett       Date:  1980-02-25       Impact factor: 4.124

7.  Diversion of ethanol metabolism by sulfhydryl amino acids. D-penicillamine-directed excretion of 2,5,5-trimethyl-D-thiazolidine-4-carboxylic acid in the urine of rats after ethanol administration.

Authors:  H T Nagasawa; D J Goon; N V Constantino; C S Alexander
Journal:  Life Sci       Date:  1975-09-01       Impact factor: 5.037

8.  Hepatic glutathione levels in D-penicillamine-fed ethanol-dependent rats.

Authors:  J M Hassing; A L Hupka; S J Stohs; P C Yoon
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1979-08

Review 9.  Ethanol--its nephrotoxic effect in the rat.

Authors:  D H Van Thiel; W D Williams; J S Gavaler; J M Little; L W Estes; B S Rabin
Journal:  Am J Pathol       Date:  1977-10       Impact factor: 4.307

10.  Effect of ethanol on glutathione concentration in isolated hepatocytes.

Authors:  J Viña; J M Estrela; C Guerri; F J Romero
Journal:  Biochem J       Date:  1980-05-15       Impact factor: 3.857
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  10 in total

1.  Zinc, ethanol, and lipid peroxidation in adult and fetal rats.

Authors:  I E Dreosti; E J Partick
Journal:  Biol Trace Elem Res       Date:  1987-12       Impact factor: 3.738

2.  Conjugation of acetaldehyde with cysteinylglycine, the first metabolite in glutathione breakdown by gamma-glutamyltranspeptidase.

Authors:  Y Kera; T Kiriyama; S Komura
Journal:  Agents Actions       Date:  1985-10

3.  Increased loss and decreased synthesis of hepatic glutathione after acute ethanol administration. Turnover studies.

Authors:  H Speisky; A MacDonald; G Giles; H Orrego; Y Israel
Journal:  Biochem J       Date:  1985-02-01       Impact factor: 3.857

4.  Antioxidant and antihyperlipidemic effect of Solanum nigrum fruit extract on the experimental model against chronic ethanol toxicity.

Authors:  Vadivel Arulmozhi; Mani Krishnaveni; Kandhan Karthishwaran; Ganesan Dhamodharan; Sankaran Mirunalini
Journal:  Pharmacogn Mag       Date:  2010-02-13       Impact factor: 1.085

5.  Time course study of the changes in blood glutathione induced by acute ethanol intoxication in the rat.

Authors:  V Fernández; N Fernández; A Valenzuela; L A Videla
Journal:  Experientia       Date:  1983-08-15

6.  The effect of alcoholic cirrhosis on the activities of microsomal aldrin epoxidase, 7-ethoxycoumarin O-de-ethylase and epoxide hydrolase, and on the concentrations of reduced glutathione in human liver.

Authors:  K W Woodhouse; F M Williams; E Mutch; P Wright; O F James; M D Rawlins
Journal:  Br J Clin Pharmacol       Date:  1983-06       Impact factor: 4.335

7.  Assessment of the scavenging action of reduced glutathione, (+)-cyanidanol-3 and ethanol by the chemiluminescent response of the xanthine oxidase reaction.

Authors:  L A Videla
Journal:  Experientia       Date:  1983-05-15

8.  Additive effect of alpha-tocopherol and ascorbic acid in combating ethanol-induced hepatic fibrosis.

Authors:  P Prathibha; S Rejitha; R Harikrishnan; S Syam Das; P A Abhilash; M Indira
Journal:  Redox Rep       Date:  2013       Impact factor: 4.412

9.  Ascorbic acid supplementation causes faster restoration of reduced glutathione content in the regression of alcohol-induced hepatotoxicity in male guinea pigs.

Authors:  P A Abhilash; R Harikrishnan; M Indira
Journal:  Redox Rep       Date:  2012       Impact factor: 4.412

10.  The Ayurvedic drug Ksheerabala (101) ameliorates alcohol-induced neurotoxicity by down-regulating the expression of transcription factor (NFkB) in rat brain.

Authors:  S Rejitha; P Prathibha; Indira Madambath
Journal:  Ayu       Date:  2015 Jul-Sep
  10 in total

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