| Literature DB >> 7194719 |
J E Morley, A S Levine, C Prasad.
Abstract
Histidyl-proline diketopiperazine was found to suppress food intake during stress-induced eating (10(-6)--10(-8) mol), starvation-induced eating (10(-8) mol) and over an 8 h period of spontaneous eating (10(-8) mol). In contrast, other cyclic piperazines failed to alter food ingestion. The suppressive effect of histidyl-proline diketopiperazine was antagonized by the enkephalin analogue, D-Ala-Met-enkephalin, in equimolar concentrations.Entities:
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Year: 1981 PMID: 7194719 DOI: 10.1016/0006-8993(81)90930-6
Source DB: PubMed Journal: Brain Res ISSN: 0006-8993 Impact factor: 3.252