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Literature DB >> 7159681

Self-replication with errors. A model for polynucleotide replication.

Abstract

A model for polynucleotide replication is presented and analyzed by means of perturbation theory. Two basic assumptions allow handling of sequences up to a chain length of v approximately 80 explicitly: point mutations are restricted to a two-digit model and individual sequences are subsumed into mutant classes. Perturbation theory is in excellent agreement with the exact results for long enough sequences (v greater than 20).

Entities: Chemical

Mesh：

Substances：
Polynucleotides

Year: 1982 PMID： 7159681 DOI： 10.1016/0301-4622(82)87037-3

Source DB: PubMed Journal: Biophys Chem ISSN： 0301-4622 Impact factor: 2.352

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Cited

62 in total

1. The role of accuracy for early stages of the origin of life.

Authors: C Blomberg
Journal: Orig Life Evol Biosph Date: 1995-06 Impact factor: 1.950

2. Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity.

Authors: A Grande-Pérez; S Sierra; M G Castro; E Domingo; P R Lowenstein
Journal: Proc Natl Acad Sci U S A Date: 2002-09-05 Impact factor: 11.205

Review 3. Viral quasispecies evolution.

Authors: Esteban Domingo; Julie Sheldon; Celia Perales
Journal: Microbiol Mol Biol Rev Date: 2012-06 Impact factor: 11.056

Self-replication with errors. A model for polynucleotide replication.

1. The role of accuracy for early stages of the origin of life.

2. Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity.

Review 3. Viral quasispecies evolution.

Review 4. Evolutionary dynamics of RNA-like replicator systems: A bioinformatic approach to the origin of life.

5. The dynamical way to mutation-selection balance of an infinite population evolving on a truncated fitness landscape.

Review 6. Examining the theory of error catastrophe.

7. Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence.

8. Protein stability imposes limits on organism complexity and speed of molecular evolution.

9. Exact solution of the Eigen model with general fitness functions and degradation rates.

10. Originator dynamics.