Literature DB >> 7133998

Identification of the cap binding protein of influenza virus.

D Blaas, E Patzelt, E Kuechler.   

Abstract

The presence of a cap binding protein in influenza virus PR8 has recently been demonstrated by photoaffinity labelling with the cap-analogue (gamma [3 2P]-[4-(benzoylphenyl)methylamido]-7-methylguanosine 5'-triphosphate). This paper describes the identification of the labelled protein using two-dimensional gel electrophoresis. The protein is shown to be PB2, the smaller of the two basic P proteins in the polymerase complex.

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Year:  1982        PMID： 7133998      PMCID： PMC321130          DOI： 10.1093/nar/10.15.4803

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  13 in total

1.  Photoactivated GTP analogs.

Authors:  A S Girshovich; V A Pozdnyakov; Y A Ovchinnikov
Journal:  Methods Enzymol       Date:  1977       Impact factor: 1.600

2.  Specificity of the photo-crosslinking reaction between poly(U) and protein S1 on the Escherichia coli ribosome.

Authors:  P Margaritella; E Kuechler
Journal:  FEBS Lett       Date:  1978-04-01       Impact factor: 4.124

3.  Synthesis and chemical properties of monomers and polymers containing 7-methylguanine and an investigation of their substrate or template properties for bacterial deoxyribonucleic acid or ribonucleic acid polymerases.

Authors:  S Hendler; E Fürer; P R Srinivasan
Journal:  Biochemistry       Date:  1970-10-13       Impact factor: 3.162

4.  [Photochemisyry of polynucleotides. 3. Study of the fluorescence of polynucleotides at ordinary temperature].

Authors:  F Pochon; M Leng; A M Michelson
Journal:  Biochim Biophys Acta       Date:  1968-12-17

5.  A simple method for the preparation of 32-P-labelled adenosine triphosphate of high specific activity.

Authors:  I M Glynn; J B Chappell
Journal:  Biochem J       Date:  1964-01       Impact factor: 3.857

6.  Ultrasensitive stain for proteins in polyacrylamide gels shows regional variation in cerebrospinal fluid proteins.

Authors:  C R Merril; D Goldman; S A Sedman; M H Ebert
Journal:  Science       Date:  1981-03-27       Impact factor: 47.728

7.  P1 and P3 proteins of influenza virus are required for complementary RNA synthesis.

Authors:  P Palese; M B Ritchey; J L Schulman
Journal:  J Virol       Date:  1977-03       Impact factor: 5.103

8.  The large P proteins of influenza A viruses are composed of one acidic and two basic polypeptides.

Authors:  M A Horisberger
Journal:  Virology       Date:  1980-11       Impact factor: 3.616

9.  Priming and inhibitory activities of RNAs for the influenza viral transcriptase do not require base pairing with the virion template RNA.

Authors:  R M Krug; B A Broni; A J LaFiandra; M A Morgan; A J Shatkin
Journal:  Proc Natl Acad Sci U S A       Date:  1980-10       Impact factor: 11.205

10.  A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription.

Authors:  S J Plotch; M Bouloy; I Ulmanen; R M Krug
Journal:  Cell       Date:  1981-03       Impact factor: 41.582
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  65 in total

1.  The replication activity of influenza virus polymerase is linked to the capacity of the PA subunit to induce proteolysis.

Authors:  B Perales; J J Sanz-Ezquerro; P Gastaminza; J Ortega; J F Santarén; J Ortín; A Nieto
Journal:  J Virol       Date:  2000-02       Impact factor: 5.103

2.  Definition of the minimal viral components required for the initiation of unprimed RNA synthesis by influenza virus RNA polymerase.

Authors:  M T Michael Lee; Konrad Bishop; Liz Medcalf; Debra Elton; Paul Digard; Laurence Tiley
Journal:  Nucleic Acids Res       Date:  2002-01-15       Impact factor: 16.971

3.  Differential activation of influenza A virus endonuclease activity is dependent on multiple sequence differences between the virion RNA and cRNA promoters.

Authors:  Michael B Leahy; Giuseppe Zecchin; George G Brownlee
Journal:  J Virol       Date:  2002-02       Impact factor: 5.103

4.  Hairpin loop structure in the 3' arm of the influenza A virus virion RNA promoter is required for endonuclease activity.

Authors:  M B Leahy; H C Dobbyn; G G Brownlee
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

5.  Activation of influenza virus RNA polymerase by the 5' and 3' terminal duplex of genomic RNA.

Authors:  M-T Michael Lee; Klaus Klumpp; Paul Digard; Laurence Tiley
Journal:  Nucleic Acids Res       Date:  2003-03-15       Impact factor: 16.971

6.  Threonine 157 of influenza virus PA polymerase subunit modulates RNA replication in infectious viruses.

Authors:  Maite Huarte; Ana Falcón; Yuri Nakaya; Juan Ortín; Adolfo García-Sastre; Amelia Nieto
Journal:  J Virol       Date:  2003-05       Impact factor: 5.103

Review 7.  Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms.

Authors:  Stéphane Boivin; Stephen Cusack; Rob W H Ruigrok; Darren J Hart
Journal:  J Biol Chem       Date:  2010-06-10       Impact factor: 5.157

8.  Identification of BPR3P0128 as an inhibitor of cap-snatching activities of influenza virus.

Authors:  John T-A Hsu; Jiann-Yih Yeh; Ta-Jen Lin; Mei-Ling Li; Ming-Sian Wu; Chung-Fan Hsieh; Yao Chieh Chou; Wen-Fang Tang; Kean Seng Lau; Hui-Chen Hung; Ming-Yu Fang; Shengkai Ko; Hsing-Pang Hsieh; Jim-Tong Horng
Journal:  Antimicrob Agents Chemother       Date:  2011-09-19       Impact factor: 5.191

9.  Minimum molecular architectures for transcription and replication of the influenza virus.

Authors:  Ayae Honda; Kiyohisa Mizumoto; Akira Ishihama
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-23       Impact factor: 11.205

10.  Mutations in the N-terminal region of influenza virus PB2 protein affect virus RNA replication but not transcription.

Authors:  Pablo Gastaminza; Beatriz Perales; Ana M Falcón; Juan Ortín
Journal:  J Virol       Date:  2003-05       Impact factor: 5.103
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