Literature DB >> 7129432

Colchicine resistance in human cell lines. Pleiotropic phenotype and decreased membrane permeability.

Y Chamla, J Bégueret.   

Abstract

Colchicine-resistant human cells were initially observed in patients exhibiting C-anaphases or tetraploidy in lymphocyte cultures. Cell lines established from these patients displayed cross-resistances to daunomycin, emetine, vinblastine, and vincristine and collateral sensitivity to Xylocaine, showing a pleiotropic phenotype similar to that described in permeability mutants in CHO cells. 3H colchicine uptake and binding assays confirmed a decreased permeability to the drug.

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Year:  1982        PMID： 7129432     DOI： 10.1007/bf00291339

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  7 in total

Review 1.  The energetics of bacterial active transport.

Authors:  R D Simoni; P W Postma
Journal:  Annu Rev Biochem       Date:  1975       Impact factor: 23.643

2.  Reduced permeability in CHO cells as a mechanism of resistance to colchicine.

Authors:  V Ling; L H Thompson
Journal:  J Cell Physiol       Date:  1974-02       Impact factor: 6.384

3.  Dominance of colchicine resistance in hybrid CHO cells.

Authors:  V Ling; R M Baker
Journal:  Somatic Cell Genet       Date:  1978-03

4.  CHO mutants resistant to colchicine, colcemid or griseofulvin have an altered beta-tubulin.

Authors:  F Cabral; M E Sobel; M M Gottesman
Journal:  Cell       Date:  1980-05       Impact factor: 41.582

5.  Altered sensitivity to cholchicine and PHA in human cultured cells.

Authors:  Y Chamla; M Roumy; M Lassègues; J Battin
Journal:  Hum Genet       Date:  1980-02       Impact factor: 4.132

6.  Mutants of Chinese hamster ovary (CHO) cells with altered colcemid-binding affinity.

Authors:  V Ling; J E Aubin; A Chase; F Sarangi
Journal:  Cell       Date:  1979-10       Impact factor: 41.582

7.  Pleiotropic phenotype of colchicine-resistant CHO cells: cross-resistance and collateral sensitivity.

Authors:  N T Bech-Hansen; J E Till; V Ling
Journal:  J Cell Physiol       Date:  1976-05       Impact factor: 6.384
  7 in total
  6 in total

1.  C-anaphases revised.

Authors:  Y Chamla
Journal:  Hum Genet       Date:  1992 Sep-Oct       Impact factor: 4.132

2.  Mitotic disturbance associated with mosaic aneuploidies.

Authors:  K Miller; W Müller; L Winkler; M R Hadam; J H Ehrich; S D Flatz
Journal:  Hum Genet       Date:  1990-03       Impact factor: 4.132

3.  C-anaphases rediscovered.

Authors:  Y Chamla
Journal:  Hum Genet       Date:  1988-05       Impact factor: 4.132

4.  Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells.

Authors:  P Gros; J Croop; I Roninson; A Varshavsky; D E Housman
Journal:  Proc Natl Acad Sci U S A       Date:  1986-01       Impact factor: 11.205

Review 5.  C-anaphases in lymphocyte cultures versus premature centromere division syndromes.

Authors:  Y Chamla
Journal:  Hum Genet       Date:  1988-02       Impact factor: 4.132

6.  A dominantly inherited cytogenetic anomaly: a possible cell division mutant.

Authors:  N L Rudd; I E Teshima; R H Martin; J E Sisken; R Weksberg
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132
  6 in total

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