Literature DB >> 566474

Dominance of colchicine resistance in hybrid CHO cells.

V Ling, R M Baker.   

Abstract

Intraspecific hybrids of colchicine-sensitive with colchicine-resistant (CHR) Chinese hamster ovary cells were constructed, using six different colchicine-resistant clones from two independent series. In each instance, colchicine resistance was expressed in an incompletely dominant manner. Some hybrid clones were examined further for the expression of the pleiotropic CHR phenotype and for the cell surface P glycoprotein. These features of the colchicine-resistant phenotype were also expressed coordinately.

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Year:  1978        PMID: 566474     DOI: 10.1007/bf01538984

Source DB:  PubMed          Journal:  Somatic Cell Genet        ISSN: 0098-0366


  16 in total

1.  Exploring the P-glycoprotein binding cavity with polyoxyethylene alkyl ethers.

Authors:  Xiaochun Li-Blatter; Anna Seelig
Journal:  Biophys J       Date:  2010-12-01       Impact factor: 4.033

Review 2.  Resistance to cytostatic drugs at the cellular level.

Authors:  C P Vendrik; J J Bergers; W H De Jong; P A Steerenberg
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

3.  Dominance of resistance to the alkylating agent 1,2:5,6-dianhydrogalactitol in P388 mouse lymphoma hybrid cells.

Authors:  I Pályi; J Bence; K Szikla; L Hullán
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

4.  Multidrug-resistant phenotype cosegregates with an amplified gene in somatic cell hybrids of drug-resistant Chinese hamster ovary cells and drug-sensitive murine cells.

Authors:  L D Teeter; J A Sanford; S Sen; R L Stallings; M J Siciliano; M T Kuo
Journal:  Mol Cell Biol       Date:  1986-12       Impact factor: 4.272

Review 5.  Multidrug resistance.

Authors:  V Ling; J Gerlach; N Kartner
Journal:  Breast Cancer Res Treat       Date:  1984       Impact factor: 4.872

6.  DNA-mediated transfer of multiple drug resistance and plasma membrane glycoprotein expression.

Authors:  P G Debenham; N Kartner; L Siminovitch; J R Riordan; V Ling
Journal:  Mol Cell Biol       Date:  1982-08       Impact factor: 4.272

7.  Co-amplification of double minute chromosomes, multiple drug resistance, and cell surface P-glycoprotein in DNA-mediated transformants of mouse cells.

Authors:  S M Robertson; V Ling; C P Stanners
Journal:  Mol Cell Biol       Date:  1984-03       Impact factor: 4.272

8.  Persistence of colchicine resistance in Ehrlich-Lettré ascites tumors and cell strains.

Authors:  C Granzow
Journal:  J Cancer Res Clin Oncol       Date:  1981       Impact factor: 4.553

9.  Multiply drug-resistant human KB carcinoma cells have decreased amounts of a 75-kDa and a 72-kDa glycoprotein.

Authors:  N Richert; S Akiyama; D Shen; M M Gottesman; I Pastan
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

Review 10.  Molecular cytogenetics of multiple drug resistance.

Authors:  P V Schoenlein
Journal:  Cytotechnology       Date:  1993       Impact factor: 2.058

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