Literature DB >> 7107845

Differential effects of Clostridium difficile toxins on tissue-cultured cells.

S T Donta, N Sullivan, T D Wilkins.   

Abstract

Two immunologically distinct Clostridium difficile toxins elicited similar morphological changes on cultured cells, although there were differences in both toxin potency and cell sensitivities.

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Year:  1982        PMID： 7107845      PMCID： PMC272271          DOI： 10.1128/jcm.15.6.1157-1158.1982

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  10 in total

1.  Classification of enterotoxins on the basis of activity in cell culture.

Authors:  G T Keusch; S T Donta
Journal:  J Infect Dis       Date:  1975-01       Impact factor: 5.226

2.  Cytotoxicity assay in antibiotic-associated colitis.

Authors:  T W Chang; M Lauermann; J G Bartlett
Journal:  J Infect Dis       Date:  1979-11       Impact factor: 5.226

3.  The growth of functional rat glial cells in a serumless medium.

Authors:  S T Donta
Journal:  Exp Cell Res       Date:  1973-11       Impact factor: 3.905

4.  Production of antitoxins to two toxins of Clostridium difficile and immunological comparison of the toxins by cross-neutralization studies.

Authors:  J M Libby; T D Wilkins
Journal:  Infect Immun       Date:  1982-01       Impact factor: 3.441

5.  Purification and characterization of toxins A and B of Clostridium difficile.

Authors:  N M Sullivan; S Pellett; T D Wilkins
Journal:  Infect Immun       Date:  1982-03       Impact factor: 3.441

6.  Effects of Clostridium difficile toxin on tissue-cultured cells.

Authors:  S T Donta; S J Shaffer
Journal:  J Infect Dis       Date:  1980-02       Impact factor: 5.226

7.  Colitis induced by Clostridium difficile.

Authors:  J G Bartlett; T Chang; N S Taylor; A B Onderdonk
Journal:  Rev Infect Dis       Date:  1979 Mar-Apr

8.  Clostridium difficile in gnotobiotic mice.

Authors:  A B Onderdonk; R L Cisneros; J G Bartlett
Journal:  Infect Immun       Date:  1980-04       Impact factor: 3.441

9.  Cytotoxic activity of Aeromonas hydrophila.

Authors:  S T Donta; A D Haddow
Journal:  Infect Immun       Date:  1978-09       Impact factor: 3.441

10.  Mucosal damage mediated by clostridial toxin in experimental clindamycin-associated colitis.

Authors:  G D Abrams; M Allo; G D Rifkin; R Fekety; J Silva
Journal:  Gut       Date:  1980-06       Impact factor: 23.059
  10 in total
  30 in total

1.  Toxin A of Clostridium difficile is a potent cytotoxin.

Authors:  K D Tucker; P E Carrig; T D Wilkins
Journal:  J Clin Microbiol       Date:  1990-05       Impact factor: 5.948

Review 2.  Clostridium difficile toxins: mechanism of action and role in disease.

Authors:  Daniel E Voth; Jimmy D Ballard
Journal:  Clin Microbiol Rev       Date:  2005-04       Impact factor: 26.132

3.  Purification of Clostridium difficile toxin A by affinity chromatography on immobilized thyroglobulin.

Authors:  H C Krivan; T D Wilkins
Journal:  Infect Immun       Date:  1987-08       Impact factor: 3.441

4.  Investigation of an outbreak of Clostridium difficile infection in a general hospital by numerical analysis of protein patterns by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

Authors:  M Costas; B Holmes; S L On; M Ganner; M C Kelly; S K Nath
Journal:  J Clin Microbiol       Date:  1994-03       Impact factor: 5.948

Review 5.  Variations in virulence and molecular biology among emerging strains of Clostridium difficile.

Authors:  Jonathan J Hunt; Jimmy D Ballard
Journal:  Microbiol Mol Biol Rev       Date:  2013-12       Impact factor: 11.056

6.  Clostridium difficile Toxins TcdA and TcdB Cause Colonic Tissue Damage by Distinct Mechanisms.

Authors:  Nicole M Chumbler; Melissa A Farrow; Lynne A Lapierre; Jeffrey L Franklin; D Borden Lacy
Journal:  Infect Immun       Date:  2016-09-19       Impact factor: 3.441

7.  Transient expression of RhoA, -B, and -C GTPases in HeLa cells potentiates resistance to Clostridium difficile toxins A and B but not to Clostridium sordellii lethal toxin.

Authors:  M Giry; M R Popoff; C von Eichel-Streiber; P Boquet
Journal:  Infect Immun       Date:  1995-10       Impact factor: 3.441

Review 8.  Clostridium difficile: clinical disease and diagnosis.

Authors:  F C Knoop; M Owens; I C Crocker
Journal:  Clin Microbiol Rev       Date:  1993-07       Impact factor: 26.132

9.  Actin-specific ADP-ribosyltransferase produced by a Clostridium difficile strain.

Authors:  M R Popoff; E J Rubin; D M Gill; P Boquet
Journal:  Infect Immun       Date:  1988-09       Impact factor: 3.441

10.  Effects of Clostridium difficile toxin B on human monocytes and macrophages: possible relationship with cytoskeletal rearrangement.

Authors:  J C Siffert; O Baldacini; J G Kuhry; D Wachsmann; S Benabdelmoumene; A Faradji; H Monteil; P Poindron
Journal:  Infect Immun       Date:  1993-03       Impact factor: 3.441
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