Literature DB >> 7105626

Central nervous system effects of aspirin.

M Fink, P Irwin.   

Abstract

The EEG effects of aspirin at single doses of 0.65 and 1.95 gm were studied in normal adult men. Compared to placebo, 1.95 gm affected the quantitative EEG, symptom self reports, and cognitive functions. The effects of 0.65 gm. were similar in direction and pattern, but failed measurable significance. The EEG profile of aspirin is distinct from that of other psychoactive substances. Its interaction with sedative substances should be considered in routine clinical use.

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Year:  1982        PMID： 7105626     DOI： 10.1038/clpt.1982.172

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  8 in total

1.  Memory-enhancing effect of aspirin is mediated through opioid system modulation in an AlCl3-induced neurotoxicity mouse model.

Authors:  Saima Rizwan; Ayesha Idrees; Muhammad Ashraf; Touqeer Ahmed
Journal:  Exp Ther Med       Date:  2016-03-11       Impact factor: 2.447

2.  Effects of peripherally and centrally acting analgesics on somato-sensory evoked potentials.

Authors:  U J Moore; V R Marsh; C H Ashton; R A Seymour
Journal:  Br J Clin Pharmacol       Date:  1995-08       Impact factor: 4.335

Review 3.  Salicylate intoxication in the elderly. Recognition and recommendations on how to prevent it.

Authors:  C Durnas; B J Cusack
Journal:  Drugs Aging       Date:  1992 Jan-Feb       Impact factor: 3.923

4.  The effect of diclofenac and ketoprofen on halothane MAC in rabbit.

Authors:  M G Rorarius; G A Baer; T Metsä-Ketelä
Journal:  Agents Actions       Date:  1993-03

Review 5.  Electroencephalography and analgesics.

Authors:  Lasse Paludan Malver; Anne Brokjaer; Camilla Staahl; Carina Graversen; Trine Andresen; Asbjørn Mohr Drewes
Journal:  Br J Clin Pharmacol       Date:  2014-01       Impact factor: 4.335

6.  Indomethacin and cognitive function in healthy elderly volunteers.

Authors:  P N Bruce-Jones; P Crome; L Kalra
Journal:  Br J Clin Pharmacol       Date:  1994-07       Impact factor: 4.335

7.  The evaluation of a nonsteroidal anti-inflammatory drug (tenoxicam) in the treatment of sleep disturbance in osteoarthritic patients.

Authors:  T J Leigh; H A Bird; I Hindmarch; V Wright
Journal:  Clin Rheumatol       Date:  1989-12       Impact factor: 2.980

8.  Diffusion of intramuscular ketoprofen into the cerebrospinal fluid.

Authors:  P Netter; F Lapicque; B Bannwarth; J N Tamisier; P Thomas; R J Royer
Journal:  Eur J Clin Pharmacol       Date:  1985       Impact factor: 2.953
  8 in total

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