Literature DB >> 7094914

Two aspects of DNA polymorphism and microheterogeneity: molecular electrostatic potential and steric accessibility.

B Pullman, R Lavery, A Pullman.   

Abstract

Polymorphism and microheterogeneity of DNA appear today as being capable of having important biological consequences. This paper presents a synthetic view of two major properties of the main known forms of DNA (A, B, alternating B, C, D and Z), namely their molecular electrostatic potentials and steric accessibilities. Variations in these properties are explained in terms of the conformational changes involved and deductions are drawn concerning their influence on the interactive properties of DNA with external agents.

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Year:  1982        PMID： 7094914     DOI： 10.1111/j.1432-1033.1982.tb06582.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN： 0014-2956


  8 in total

Review 1.  Molecular recognition: models for drug design.

Authors:  R J Breckenridge
Journal:  Experientia       Date:  1991-12-01

2.  Theoretical study of the sequence specificity in the covalent binding of the antitumor drug CC-1065 to DNA.

Authors:  K Zakrzewska; M Randrianarivelo; B Pullman
Journal:  Nucleic Acids Res       Date:  1987-07-24       Impact factor: 16.971

3.  Anthracycline-binding induced DNA stiffening, bending and elongation; stereochemical implications from viscometric investigations.

Authors:  K E Reinert
Journal:  Nucleic Acids Res       Date:  1983-05-25       Impact factor: 16.971

4.  DNA bending by small, mobile multivalent cations.

Authors:  I Rouzina; V A Bloomfield
Journal:  Biophys J       Date:  1998-06       Impact factor: 4.033

5.  Sequence-dependent DNA condensation and the electrostatic zipper.

Authors:  J C Sitko; E M Mateescu; H G Hansma
Journal:  Biophys J       Date:  2003-01       Impact factor: 4.033

6.  DNA conformational analysis in solution by uranyl mediated photocleavage.

Authors:  P E Nielsen; N E Møllegaard; C Jeppesen
Journal:  Nucleic Acids Res       Date:  1990-07-11       Impact factor: 16.971

Review 7.  Molecular electrostatic potentials: an effective tool for the elucidation of biochemical phenomena.

Authors:  P Politzer; P R Laurence; K Jayasuriya
Journal:  Environ Health Perspect       Date:  1985-09       Impact factor: 9.031

8.  Recognition of the spliceosomal branch site RNA helix on the basis of surface and electrostatic features.

Authors:  Darui Xu; Nancy L Greenbaum; Marcia O Fenley
Journal:  Nucleic Acids Res       Date:  2005-02-23       Impact factor: 16.971
  8 in total

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