Literature DB >> 704357

Sequence organization of the beta-globin mRNA precursor.

K Smith, J B Lingrel.   

Abstract

The sequence organization of the beta-globin mRNA precursor has been determined directly by analyzing the resistant fragments from the RNase A digestion of the precursor RNA-globin cDNA hybrid. Three fragments are obtained which proves that the beta-globin mRNA sequence in its precursor is split into three discontinuous segments. The two intervening sequences in the beta-globin gene are therefore transcribed and removed during mRNA maturation.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 704357      PMCID： PMC342249          DOI： 10.1093/nar/5.9.3295

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  13 in total

1.  A precursor of globin messenger RNA.

Authors:  J Ross
Journal:  J Mol Biol       Date:  1976-09-15       Impact factor: 5.469

2.  Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.

Authors:  S M Tilghman; D C Tiemeier; J G Seidman; B M Peterlin; M Sullivan; J V Maizel; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1978-02       Impact factor: 11.205

3.  Variable and constant parts of the immunoglobulin light chain gene of a mouse myeloma cell are 1250 nontranslated bases apart.

Authors:  C Brack; S Tonegawa
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

4.  Purification of globin messenger RNA from dimethylsulfoxide-induced Friend cells and detection of a putative globin messenger RNA precursor.

Authors:  P J Curtis; C Weissmann
Journal:  J Mol Biol       Date:  1976-10-05       Impact factor: 5.469

5.  The location of the globin mRNA sequence within its 16S precursor.

Authors:  K Smith; P Rosteck; J B Lingrel
Journal:  Nucleic Acids Res       Date:  1978-01       Impact factor: 16.971

6.  Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

Authors:  G K McMaster; G G Carmichael
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

7.  The rabbit beta-globin gene contains a large large insert in the coding sequence.

Authors:  A J Jeffreys; R A Flavell
Journal:  Cell       Date:  1977-12       Impact factor: 41.582

8.  The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor.

Authors:  S M Tilghman; P J Curtis; D C Tiemeier; P Leder; C Weissmann
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

9.  Presence of a putative 15S precursor to beta-globin mRNA but not to alpha-globin mRNA in Friend cells.

Authors:  P J Curtis; N Mantei; J van den Berg; C Weissmann
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205

10.  Purification of a putative precursor of globin messenger RNA from mouse nucleated erythroid cells.

Authors:  S P Kwan; T G Wood; J B Lingrel
Journal:  Proc Natl Acad Sci U S A       Date:  1977-01       Impact factor: 11.205
View more
  4 in total

1.  Mapping of RNA by a modification of the Berk-Sharp procedure: the 5' termini of 15 S beta-globin mRNA precursor and mature 10 s beta-globin mRNA have identical map coordinates.

Authors:  R F Weaver; C Weissmann
Journal:  Nucleic Acids Res       Date:  1979-11-10       Impact factor: 16.971

2.  Comparison of cloned mouse alpha- and beta-globin genes: conservation of intervening sequence locations and extragenic homology.

Authors:  A Leder; H I Miller; D H Hamer; J G Seidman; B Norman; M Sullivan; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

3.  Unusual alpha-globin-like gene that has cleanly lost both globin intervening sequences.

Authors:  Y Nishioka; A Leder; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1980-05       Impact factor: 11.205

4.  Messenger RNA processing and nuclear structure: isolation of nuclear ribonucleoprotein particles containing beta-globin messenger RNA precursors.

Authors:  T Pederson; N G Davis
Journal:  J Cell Biol       Date:  1980-10       Impact factor: 10.539
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.