| Literature DB >> 7043053 |
R J Hené, P Boer, H A Koomans, E J Mees.
Abstract
The disagreement in the literature concerning the role of aldosterone in the maintenance of potassium homeostasis in chronic renal disease might be partially explained by differences in plasma renin activity (PRA) among individual patients. Therefore, a study was done in 28 selected patients with varying degrees of renal insufficiency whose serum potassium and PRA concentrations were within the normal range. The results indicate that at comparable serum potassium and PRA concentrations, plasma aldosterone is in most instances elevated when creatinine clearance is lower than 50% of normal.Entities:
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Year: 1982 PMID: 7043053 DOI: 10.1038/ki.1982.14
Source DB: PubMed Journal: Kidney Int ISSN: 0085-2538 Impact factor: 10.612