Literature DB >> 6999128

The use of choline chloride in ataxic disorders.

C M Lawrence, P Millac, G S Stout, J W Ward.   

Abstract

Fourteen patients with a variety of ataxic disorders were given choline chloride, double blind for six weeks, in an attempt to improve gait and manual dexterity. One patient withdrew before receiving the active drug, twelve patients showed no functional improvement, but one achieved greater mobility; his response, which was dose dependent, ceased when choline was stopped and was reproducible.

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Year:  1980        PMID: 6999128      PMCID: PMC490574          DOI: 10.1136/jnnp.43.5.452

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  5 in total

1.  A simple radioenzymatic procedure for the determination of choline and acetylcholine in brain regions of rats sacrificed by microwave irradiation.

Authors:  S A Eckernäs; S M Aquilonius
Journal:  Acta Physiol Scand       Date:  1977-08

2.  Oral choline in cerebellar ataxia.

Authors:  N J Legg
Journal:  Br Med J       Date:  1978-11-18

3.  Brain acetylcholine: control by dietary choline.

Authors:  E L Cohen; R J Wurtman
Journal:  Science       Date:  1976-02-13       Impact factor: 47.728

4.  Lecithin consumption raises serum-free-choline levels.

Authors:  R J Wurtman; M J Hirsch; J H Growdon
Journal:  Lancet       Date:  1977-07-09       Impact factor: 79.321

5.  Physostigmine in familial ataxias.

Authors:  R A Kark; J P Blass; M A Spence
Journal:  Neurology       Date:  1977-01       Impact factor: 9.910

  5 in total
  6 in total

Review 1.  Pharmacological treatments of cerebellar ataxia.

Authors:  Masafumi Ogawa
Journal:  Cerebellum       Date:  2004       Impact factor: 3.847

2.  Comprehensive systematic review summary: Treatment of cerebellar motor dysfunction and ataxia: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.

Authors:  Theresa A Zesiewicz; George Wilmot; Sheng-Han Kuo; Susan Perlman; Patricia E Greenstein; Sarah H Ying; Tetsuo Ashizawa; S H Subramony; Jeremy D Schmahmann; K P Figueroa; Hidehiro Mizusawa; Ludger Schöls; Jessica D Shaw; Richard M Dubinsky; Melissa J Armstrong; Gary S Gronseth; Kelly L Sullivan
Journal:  Neurology       Date:  2018-02-09       Impact factor: 9.910

Review 3.  Choline intake and its dietary reference values in Korea and other countries: a review.

Authors:  Eugene Shim; Eunju Park
Journal:  Nutr Res Pract       Date:  2022-04-18       Impact factor: 1.992

4.  Low dose choline chloride in cerebellar degeneration.

Authors:  C A Austin; K I Mundy; S Dorey
Journal:  J Neurol Neurosurg Psychiatry       Date:  1984-09       Impact factor: 10.154

Review 5.  Phospholipase D and Choline Metabolism.

Authors:  Fredrick O Onono; Andrew J Morris
Journal:  Handb Exp Pharmacol       Date:  2020

6.  Choline: The Underconsumed and Underappreciated Essential Nutrient.

Authors:  Taylor C Wallace; Jan Krzysztof Blusztajn; Marie A Caudill; Kevin C Klatt; Elana Natker; Steven H Zeisel; Kathleen M Zelman
Journal:  Nutr Today       Date:  2018-11-13
  6 in total

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