Literature DB >> 6481372

Low dose choline chloride in cerebellar degeneration.

C A Austin, K I Mundy, S Dorey.   

Abstract

Sixteen patients with cerebellar degeneration were treated with oral choline chloride for six weeks at doses of 3 and 6 g daily. Two patients improved with choline but another four improved with placebo. Choline chloride in a dose of 3-6 g daily is no better than placebo in improving ataxia due to cerebellar degeneration.

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Year:  1984        PMID： 6481372      PMCID： PMC1028011          DOI： 10.1136/jnnp.47.9.1038

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  7 in total

1.  Choline in hereditary ataxia.

Authors:  D V Philcox; B Kies
Journal:  Br Med J       Date:  1979-09-08

2.  Brain acetylcholine: control by dietary choline.

Authors:  E L Cohen; R J Wurtman
Journal:  Science       Date:  1976-02-13       Impact factor: 47.728

3.  Letter: Plasma concentration of free choline in patients with Huntington's chorea on high doses of choline chloride.

Authors:  S M Aquilonius; S A Eckernäs
Journal:  N Engl J Med       Date:  1975-11-20       Impact factor: 91.245

4.  Huntington's disease: clinical and chemical effects of choline administration.

Authors:  J H Growdon; E L Cohen; R J Wurtman
Journal:  Ann Neurol       Date:  1977-05       Impact factor: 10.422

5.  Pharmacological investigations of the cholinergic imbalance hypotheses of movement disorders and psychosis.

Authors:  K L Davis; P A Berger
Journal:  Biol Psychiatry       Date:  1978-02       Impact factor: 13.382

6.  Plasma concentrations of choline in man following choline chloride.

Authors:  L E Hollister; D J Jenden; J R Amaral; J D Barchas; K L Davis; P A Berger
Journal:  Life Sci       Date:  1978-07-03       Impact factor: 5.037

7.  The use of choline chloride in ataxic disorders.

Authors:  C M Lawrence; P Millac; G S Stout; J W Ward
Journal:  J Neurol Neurosurg Psychiatry       Date:  1980-05       Impact factor: 10.154
  7 in total
  1 in total

1.  Comprehensive systematic review summary: Treatment of cerebellar motor dysfunction and ataxia: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.

Authors:  Theresa A Zesiewicz; George Wilmot; Sheng-Han Kuo; Susan Perlman; Patricia E Greenstein; Sarah H Ying; Tetsuo Ashizawa; S H Subramony; Jeremy D Schmahmann; K P Figueroa; Hidehiro Mizusawa; Ludger Schöls; Jessica D Shaw; Richard M Dubinsky; Melissa J Armstrong; Gary S Gronseth; Kelly L Sullivan
Journal:  Neurology       Date:  2018-02-09       Impact factor: 9.910
  1 in total

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